AI Article Synopsis
- - The study aimed to analyze the relationship between various blood markers (like IMA, CRP, ESR, WBC count, NLR, PLR, and MPV) and appendicitis in children.
- - It included 63 patients (30 with appendicitis and 33 healthy controls) and found IMA to be the most effective marker for diagnosing appendicitis, with an area under the curve (AUC) of 0.991.
- - The study concluded that combining NLR, PLR, IMA, and ESR with traditional symptoms and imaging may improve the diagnosis of appendicitis.
Article Abstract
Background: The aim of the present study was to determine relationship of ischemia-modified albumin (IMA) level, C-reactive protein (CRP) level, erythrocyte sedimentation rate (ESR), white blood cell (WBC) count, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and mean platelet volume (MPV) to appendicitis in children.
Methods: Study included total of 63 patients who presented at hospital between May 2015 and November 2015. Of these, 30 were cases of appendicitis, and 33 were healthy control subjects. The groups were statistically similar in age and gender.
Results: Receiver operating characteristic curve was evaluated for IMA, CRP, ESR, WBC, MPV, NLR, and PLR values in patients with appendicitis, and IMA was determined to have highest area under the curve value (0.991), followed by NLR (0.946), CRP (0.808), PLR (0.779), ESR (0.767), WBC (0.749), and MPV (0.583).
Conclusion: Use of NLR, PLR, IMA, and ESR values may be helpful in diagnosis of appendicitis, in addition to WBC and CRP values, lower right quadrant abdominal pain, and ultrasonography signs commonly used.
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| http://dx.doi.org/10.5505/tjtes.2016.11823 | DOI Listing |
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