Constructal law analysis of Cl transport in eyes aqueous humor.

Sci Rep

Dipartimento di Oculistica, Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo, Via Venezia 7, 15121, Alessandria, Italy.

Published: July 2017

Progressive loss-of-vision related to any intraocular disorder is known as glaucoma. Secretion of aqueous humor is physiologically important to provide nutrients and oxygen to the avascular anterior segment and ensuring normal visual function, even if, nowadays reducing the secretory rate to lower intraocular pressure is a major strategy in treating glaucomatous patients. Understanding the mechanisms and regulation of aqueous humor formation is very important to develop possible new approaches to lower intraocular pressure,but today there isn't any comprehensive model of the regulation of these component in forming aqueous humor. In this paper Construcal law is used to suggest how the Cl fluxes can determine the water inflow and outflow, and, consequently, how the intraocular pressure is controlled by these fluxes.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537270PMC
http://dx.doi.org/10.1038/s41598-017-07357-8DOI Listing

Publication Analysis

Top Keywords

aqueous humor
16
lower intraocular
8
intraocular pressure
8
constructal law
4
law analysis
4
analysis transport
4
transport eyes
4
aqueous
4
eyes aqueous
4
humor
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!