Objective: Discrepancy analyses refer to comparison methods that evaluate the relationship or differences between two measures in the same individual. A common type of discrepancy analysis involves the comparison of two trials within a measure, such as, Trails A and B of the Trail Making Test (TMT). The TMT is well-suited to this role as the two measures are highly correlated, assess similar underlying constructs, and most importantly demonstrate differential vulnerability to the impact of pathology. While the inclusion of these types of data in the form of difference scores or ratios has become more frequent, this information has been presented only for demographically adjusted subgroups and has not taken into account the level of performance of the comparison trial, Trails A.
Method: The role and advantages of discrepancy analysis with the TMT stratified by level of Trails A performance were demonstrated with an Australian normative sample of 647 participants and a heterogeneous clinical sample consisting of 2,292 Australian and U.S.
Results: The ability to differentiate between the influence of slowed visual scanning and/or graphomotor speed, and reduced mental flexibility was demonstrated by applying the normative data to clinical case discrepancies. The importance of accounting for the variability in discrepancy scores associated with the level of performance of Trails A was also highlighted.
Conclusion: A simple, efficient, and effective approach to examining the basis for differences between TMT-A and TMT-B performances is provided to examine the relative contributions of perceptual/motor abilities, and mental flexibility.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1080/13854046.2017.1357756 | DOI Listing |
J Coll Physicians Surg Pak
January 2025
Department of Oral and Maxillofacial Surgery, Frontier Medical and Dental College, Abbottabad, Pakistan.
Objective: To establish the construct validity of the Assessment Implementation Measures (AIM) tool to accurately assess faculty perspectives on implemented assessment systems, facilitating the alignment with set standards.
Study Design: Qualitative Study. Place and Duration of the Study: The study was carried out at RIPHAH International University and data were collected from participants (senior faculty members) involved in teaching and assessment of undergraduates from various medical and dental colleges in Pakistan.
Hum Genomics
January 2025
Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Richards Building B304, 3700 Hamilton Walk, Philadelphia, PA, 19104, USA.
Background: Disease comorbidities and longer-term complications, arising from biologically related associations across phenotypes, can lead to increased risk of severe health outcomes. Given that many diseases exhibit sex-specific differences in their genetics, our objective was to determine whether genotype-by-sex (GxS) interactions similarly influence cross-phenotype associations. Through comparison of sex-stratified disease-disease networks (DDNs)-where nodes represent diseases and edges represent their relationships-we investigate sex differences in patterns of polygenicity and pleiotropy between diseases.
View Article and Find Full Text PDFBMC Health Serv Res
January 2025
Department of Paediatrics, Children's National Hospital, Washington DC, USA.
Background: Caregiver concern is the main driver to paediatric emergency departments visits. Understanding caregiver worries is crucial to guide patients to the most appropriate healthcare setting. Previous research shows mixed findings on the accordance between caregiver assessment and professional triage.
View Article and Find Full Text PDFClin Rheumatol
January 2025
Department of Dentistry-Division of Oral Medicine, Oral Pathology and Radiology, and Division of Dental Hygiene, Faculty of Medicine and Dentistry, University of Alberta, Room 5-357 Edmonton Clinic Health Academy, 11405 87 Avenue NW, Edmonton, AB, Canada.
Introduction: Sjögren's syndrome (SS) presents complex diagnostic challenges due to its multi-organ involvement, often leading to misdiagnosis, which can result in unnecessary treatments, elevated healthcare costs, and significant impacts on patient quality of life. Accurate diagnosis is therefore critical, utilising ACR/EULAR criteria that include both labial minor salivary gland (LMSG) biopsy and anti-SSA antibodies.
Methods: This retrospective study analysed medical records of 87 adults suspected of primary SS, who underwent both anti-SSA serology and LMSG biopsy.
Br J Sports Med
January 2025
Department of Clinical Medicine, Aarhus University Department of Clinical Medicine, Aarhus, Midtjylland, Denmark.
Objective: Validated patient-reported outcome measures for patients with hip-abductor tendon pathology are lacking. Recent studies indicate that the Copenhagen Hip and Groin Outcome Score (HAGOS), in the original or the revised scoring format, and the Oxford Hip Score (OHS) may be relevant for use in patients with hip-abductor tendon pathology. The objective of this study was to assess the validity of the Danish version of the HAGOS, the revised HAGOS, and the OHS psychometrically in patients with hip-abductor tendon pathology.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!