AI Article Synopsis

  • Over the last ten years, new treatments for non-small cell lung cancer adenocarcinoma have emerged based on pharmacogenomics, highlighting the importance of specific genetic tests in everyday clinical practice.
  • Key genetic factors to investigate include mutations in the epidermal growth factor receptor, anaplastic lymphoma kinase, and programmed death-ligand 1 to guide therapy choices for cancer patients.
  • The case series will discuss the adverse effects experienced by patients treated with the immunotherapies nivolumab and pembrolizumab, along with insights on their treatment and follow-up care.

Article Abstract

In the past decade novel agents are on the market for non-small cell lung cancer adenocarcinoma based on pharmacogenomics. The epidermal growth factor receptor mutation, anaplastic lymphoma kinase and programmed death-ligand 1 investigation is necessary in the everyday clinical practice for the oncologic patient. Immunotherapy is nowadays the novel therapy for advanced stage non-small cell lung cancer with two agents nivolumab and pembrolizumab. In the current case series we will present adverse effects from our centers and comment on the treatment and follow-up of the patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519224PMC
http://dx.doi.org/10.1016/j.rmcr.2017.07.004DOI Listing

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