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Comparative safety of transvenous and leadless pacemakers in patients with cardiovascular diseases: A meta-analysis study.
Heliyon
January 2025
Faculty of Medicine and Medical Sciences, University of Balamand, Kalhat, Lebanon.
Background: Transvenous pacemakers (TVP) and leadless pacemakers (LP) are two reliable permanent modalities for the treatment of heart rhythm disorders. Several observational studies explored the safety and efficacy of the two devices. The aim of this meta-analysis study is to present a comparative analysis of the safety of leadless versus transvenous pacemakers.
View Article and Find Full Text PDFPhase 1b/2a safety study of lemborexant as an adjunctive treatment for insomnia to buprenorphine-naloxone for opioid use disorder: A randomized controlled trial.
Drug Alcohol Depend Rep
March 2025
Institute for Drug and Alcohol Studies, Virginia Commonwealth University, 203 East Cary Street, Richmond, VA 23219, USA.
Background: Evidence supports the common incidence of sleep disturbance in opioid use disorder (OUD) as a potential marker of disrupted orexin system functioning. This study evaluated the initial safety and tolerability of a challenge dose of lemborexant, a dual orexin antagonist, as an adjunct to buprenorphine/naloxone.
Methods: Patients (18-65 years old) with OUD receiving sublingual buprenorphine/naloxone, with a Pittsburgh Sleep Quality Index total score of 6 or higher, were recruited from outpatient clinics.
Differences in Physiological Responses Between Two Repeated Sprint Protocols in Female Soccer Players.
Int J Exerc Sci
December 2024
Section of Sports Medicine, Department of Community & Rehabilitation, Umeå University, SWEDEN.
Soccer is a team sport characterized by repeated high-intensity sprints followed by brief periods of recovery. Repeated sprints with (RCOD) and without (RSA) change-of-direction has therefore been recognized as an important fitness component. The purpose of the present study was to examine the differences in physiological responses between RSA and RCOD, and the relationship with Yo-Yo intermittent recovery test (YYIR1), as an estimate of aerobic capacity, in female soccer players.
View Article and Find Full Text PDFStrategic Management of Valve Infolding in Evolut TAVR Procedures: Enhancing Outcomes and Ensuring Patient Safety.
J Soc Cardiovasc Angiogr Interv
December 2024
Cardiovascular Institute, Detroit Medical Center, DMC Heart Hospital, Detroit, Michigan.
Transcatheter aortic valve repair (TAVR) presents a minimally invasive alternative to traditional surgical valve replacement, albeit not without its own set of complications. A rare complication is the infolding of the self-expanding valve, which can precipitate cardiac arrest. The estimated incidence rate of this complication stands at 1.
View Article and Find Full Text PDFIncidental imaging detection of Kartagener syndrome in a female: A case report.
Radiol Case Rep
March 2025
Department of Radiology and Imaging, Grande International Hospital, Kathmandu, Nepal.
Kartagener syndrome is a rare ciliopathic genetic disorder characterized by a triad of chronic sinusitis, situs inversus, and bronchiectasis. The underlying pathophysiology involves reduced ciliary motility due to defects in ciliary structure and function within the respiratory tract and fallopian tubes. Diagnosis is typically confirmed through imaging studies such as X-rays, CT scans, and echocardiograms, which reveal the abnormal orientation of the heart and other organs.
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