AI Article Synopsis
- Surveillance of drug safety post-marketing involves various methods, including provider reports and electronic records, but there are challenges in effectiveness and costs.
- A new data-mining tool from Sysomos analyzed Facebook mentions of statins and related side effects over a month, revealing that 4.3% of mentions included these side effects.
- While this percentage aligns with estimates of side effects in patients, the limitations of the tool, particularly a lack of full-text mining, hinder precise content analysis and categorization.
Article Abstract
Introduction: Surveillance of the safety of prescribed drugs after marketing approval has been secured remains fraught with complications. Formal ascertainment by providers and reporting to adverse-event registries, formal surveys by manufacturers, and mining of electronic medical records are all well-known approaches with varying degrees of difficulty, cost, and success. Novel approaches may be a useful adjunct, especially approaches that mine or sample internet-based methods such as online social networks.
Methods: A novel commercial software-as-a-service data-mining product supplied by Sysomos from Datasift/Facebook was used to mine all mentions on Facebook of statins and stain-related side effects in the US in the 1-month period 9 January 2017 through 8 February 2017.
Results: A total of 4.3% of all 25,700 mentions of statins also mentioned typical stain-related side effects. Multiple methodological weaknesses stymie interpretation of this percentage, which is however not inconsistent with estimates that 5-20% of patients taking statins will experience typical side effects at some time.
Conclusions: Future work on pharmacovigilance may be informed by this novel commercial tool, but the inability to mine the full text of a posting poses serious challenges to content categorization.
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| http://dx.doi.org/10.1007/s40264-017-0577-3 | DOI Listing |
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