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Invasive aspergillosis in an immunocompetent patient: A retrospective case report and review of the literature.
J Infect Dev Ctries
November 2024
Department of Neurosurgery, Shaoxing People's Hospital, Zhejiang, 312000, China.
Introduction: Invasive aspergillosis (IA) is rare in immunocompetent patients. We present the case of a 44-year-old female with IA invading the lungs, mediastinum, heart, and brain, with a disease duration of 11 years.
Case Presentation: The patient was initially diagnosed with lung aspergillosis that had invaded the mediastinum on October 8, 2008.
Directional versus ring-mode deep brain stimulation for Parkinson's disease: protocol of a multi-centre double-blind randomised crossover trial.
BMC Neurol
October 2023
Amsterdam UMC, University of Amsterdam, Neurology, Meibergdreef 9, Amsterdam, Netherlands.
Background: The effectiveness of Deep Brain Stimulation (DBS) therapy for Parkinson's disease can be limited by side-effects caused by electrical current spillover into structures adjacent to the target area. The objective of the STEEred versus RING-mode DBS for Parkinson's disease (STEERING) study is to investigate if directional DBS for Parkinson's disease results in a better clinical outcome when compared to ring-mode DBS.
Methods: The STEERING study is a prospective multi-centre double-blind randomised crossover trial.
Food as a Driver of a Cholera Epidemic in Jijiga, Ethiopia-June 2017.
Am J Trop Med Hyg
May 2023
Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
We conducted a case-control study to identify risk and protective factors during a cholera outbreak in Jijiga, Ethiopia, in June 2017. A case-patient was defined as anyone > 5 years old with at least three loose stools in 24 hours who was admitted to a cholera treatment center in Jijiga on or after June 16, 2017. Two controls were matched to each case by type of residency (rural or urban) and age group.
View Article and Find Full Text PDFAlzheimer Disease Blood Biomarkers in Patients With Out-of-Hospital Cardiac Arrest.
JAMA Neurol
April 2023
Department of Psychiatry and Neurochemistry, Institute of Neuroscience & Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.
Article Synopsis
- The study investigates if blood levels of phosphorylated tau (p-tau) and amyloid-β peptides (Aβ) can serve as biomarkers for predicting neurological outcomes in patients who have experienced cardiac arrest.
- Researchers conducted a clinical biobank study involving 717 unconscious cardiac arrest patients, comparing blood biomarker levels taken at different times after the event with neural injury markers.
- Results from this study could help distinguish between patients with good and poor neurological outcomes, potentially aiding in more effective prognostication after cardiac arrest.
[The study of mitochondrial disorder pedigree associated with FASTKD2 variants and uniparental disomy].
Zhonghua Yi Xue Za Zhi
January 2023
Department of Central Laboratory, Peking University First Hospital, Beijing 100034, China.
To analyse the genetic cause of a proband with mitochondrial disease caused by FASTKD2 gene variation and uniparental disomy. Detailed medical history of a child suspected "mitochondrial disease" were inquired in Peking University First Hospital on November 23, 2017. c.
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