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promotes synchronous multiple primary lung cancer progression through apoptosis regulation.
Front Immunol
January 2025
Faculty of Life and Biotechnology, Kunming University of Science and Technology, Kunming, China.
Background: Dysbiosis of the lung microbiome can contribute to the initiation and progression of lung cancer. Synchronous multiple primary lung cancer (sMPLC) is an increasingly recognized subtype of lung cancer characterized by high morbidity, difficulties in early detection, poor prognosis, and substantial clinical challenges. However, the relationship between sMPLC pathogenesis and changes in the lung microbiome remains unclear.
View Article and Find Full Text PDFPrevalence of nasopharyngeal bacteria during naturally occurring bovine respiratory disease in commercial stocker cattle.
PeerJ
January 2025
Department of Animal Science, University of Tennessee-Knoxville, Knoxville, TN-Tennessee, United States.
Bovine respiratory disease (BRD) is one of the most common economic and health challenges to the beef cattle industry. Prophylactic use of antimicrobial drugs can alter the microbial communities in the respiratory tract. Considering that the bovine upper respiratory tract microbiome has been associated with generalized health, understanding the microenvironment that influences this microbiome may provide insights into the pathogenesis of BRD.
View Article and Find Full Text PDFThe bronchopleural fistula (BPF) is a pathological passageway between the bronchus and the pleural cavity. Diagnosing and localising BPF can be challenging, and the traditional retrograde methylene blue (MB) perfusion method may fail to identify multifocal BPFs. This article reports a novel method for locating multifocal BPFs in patients undergoing concurrent empyema debridement.
View Article and Find Full Text PDFPiloting a battery to evaluate parasympathetic reactivity and externalizing behaviours during early childhood in autism spectrum disorder.
Infant Child Dev
April 2024
Division of Developmental Medicine, Boston Children's Hospital, Boston, MA, United States.
Background: Respiratory Sinus Arrhythmia Reactivity (RSA-R) correlates both positively and negatively with externalizing behavior in autistic individuals. These inconsistencies may result from task-based differences. This pilot study measured RSA-R in 4-to 6-year-olds, across two time-points, using four validated tasks with matched baseline and challenge periods.
View Article and Find Full Text PDFACCREDIT: Validation of clinical score for progression of COVID-19 while hospitalized.
Glob Epidemiol
June 2025
Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Brazil.
Unlabelled: COVID-19 is no longer a global health emergency, but it remains challenging to predict its prognosis.
Objective: To develop and validate an instrument to predict COVID-19 progression for critically ill hospitalized patients in a Brazilian population.
Methodology: Observational study with retrospective follow-up.
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