Anthropogenic heat flux (Q), which originates through energy consumption from buildings, industrial plants, vehicle exhausts, and human metabolism releases, is an important component in the urban Surface Energy Balance (SEB) system, and is key to understanding of many urban environmental issues. The present study provided a hybrid Q modeling approach, which combined the inventory and GIS approach to create a 365-day hourly Q profile at 120 m spatial resolution in Los Angeles County, California, USA. Q was estimated by separate calculation of heat release from buildings, traffics, and human metabolism, respectively. The results indicated that Q showed different magnitudes and diurnal patterns between workdays (dual-peak shape) and weekends/holidays, and also varied with seasons, and land use types. Qf yielded the highest values in the summer workdays, with its maximum value of 7.76 w/m. Q in hot summer workdays was obviously higher than that in the average summer workdays, which caused by higher demands for space cooling in buildings, and can reach 8.14 w/m at maximum. Building energy consumption was identified as the dominant contributor to the Q in Downtown Los Angeles, which was found to have the largest mean Q throughout the year among all neighborhoods. It can be concluded that Q in the downtown was more significant in workdays than that in non-workdays, and its maximum value can reach 100 w/m. It is suggested that our approach may have wider applicability for Q estimation in large areas compared with the existing studies, as all the data used were available to the public. A high spatial and temporal Q profile, which can readily be incorporated into urban energy balance and Urban Heat Island (UHI) studies, provides valuable data and information for pertinent government agencies and researchers.
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http://dx.doi.org/10.1016/j.jenvman.2017.07.047 | DOI Listing |
JAMA Netw Open
March 2025
Department of Neurology, Dell Medical School, The University of Texas at Austin.
Importance: Tenecteplase is an alternative to alteplase for emergency treatment of acute ischemic stroke. However, limited data are available comparing their clinical effectiveness in routine clinical practice.
Objective: To compare short-term effectiveness and safety outcomes for patients with ischemic stroke treated with intravenous tenecteplase vs alteplase.
Aging Dis
March 2025
Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, California 90095, USA.
Aging leads to a decline in physiological functions and increased risk of mortality, yet therapeutic avenues are limited. Dietary phytochemicals provide an attractive approach to counteract age-related health decline. Here, we have examined the impact of feeding extracts of rosemary and ginger, prepared via three different extraction methods, on markers of aging and healthspan in the fruit fly Drosophila.
View Article and Find Full Text PDFInt J Surg
March 2025
Center for Medical Research on Innovation and Translation, Guangzhou First People' s Hospital, the Second Afffliated Hospital of South China University of Technology, Guangzhou, Guangdong, China.
Clin Cancer Res
March 2025
Hospital for Sick Children, Toronto, Ontario, Canada.
Li-Fraumeni syndrome (LFS) is an autosomal dominant cancer predisposition condition characterized by a high lifetime risk for a wide spectrum of malignancies associated with germline pathogenic/likely pathogenic (P/LP) variants in the TP53 tumor suppressor gene. Secondary malignant neoplasms are particularly common. Early cancer detection through surveillance enables early intervention and leads to improved clinical outcomes with reduced tumor-related mortality and treatment-related morbidity.
View Article and Find Full Text PDFAm J Respir Crit Care Med
March 2025
University of Iowa, Radiology and Biomedical Engineering, Iowa City, Iowa, United States;
Rationale: Quantifying functional small airways disease (fSAD) requires additional expiratory computed tomography (CT) scan, limiting clinical applicability. Artificial intelligence (AI) could enable fSAD quantification from chest CT scan at total lung capacity (TLC) alone (fSAD).
Objectives: To evaluate an AI model for estimating fSAD, compare it with dual-volume parametric response mapping fSAD (fSAD), and assess its clinical associations and repeatability in chronic obstructive pulmonary disease (COPD).
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