Sera obtained from 3,472 persons in Malaysia, Thailand, Philippines and Indonesia were tested for the presence of antibody to adult T-cell leukemia-associated antigen by the gelatin particle agglutination test and indirect immunofluorescence. Among these, only two seropositives were identified. One was a 30-year-old male Malaysian of Indian origin. The other was a 42-year-old female Thai who resided in Bangkok. These results suggested that the infection of human T-lymphotropic virus type 1 might not be endemic in these countries.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.7883/yoken1952.39.25 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Seroprevalence of Strongyloides stercoralis, human T-lymphotropic virus, and Chagas disease in the Peruvian Amazon: a cross-sectional study.
Rev Inst Med Trop Sao Paulo
December 2024
Hospital Universitario General Dr. Balmis, Departamento de Medicina Interna, Alicante, Spain.
Strongyloides stercoralis infections, human T-lymphotropic virus (HTLV) infections, and Chagas diseases occur throughout many regions of Central and South America, including Peru. This study aimed to evaluate the seroprevalence of S. stercoralis, HTLV, and Chagas disease in Iquitos (Peruvian Amazon) and the associated epidemiological conditions for S.
View Article and Find Full Text PDFDeclining trend of HTLV-1 among organ/ tissue donors in Iranian Tissue Bank between 2014-2021.
Retrovirology
December 2024
Iranian Tissue Bank and Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Article Synopsis
- HTLV-1 is linked to serious health issues like Adult T-cell Leukemia/Lymphoma and HAM/TSP; thus, screening potential organ donors for the virus is vital due to high transmission risks, particularly in kidney transplant recipients.
- A study at the Iranian Tissue Bank from 2014 to 2021 found that 3% of 3,814 potential organ/tissue donors tested positive for HTLV-1, with rates significantly dropping from 6% to 0.5% over the years.
- Females showed a higher positivity rate (4%) than males (2%), and donors with brain death had a much lower infection rate (0.2%) compared to those with circulatory death (4%).
Human T-Lymphotropic Virus-1 Associated With Adult T-Cell Lymphoma: A Case Report.
Cureus
November 2024
Odontology, Pitié-Salpêtrière Hospital, Paris, FRA.
Human T-cell lymphotropic virus 1 (HTLV-1) was subsequently identified as the cause of adult T-cell leukemia/lymphoma (ATLL). While oral manifestations of this disease have been documented, they remain poorly described in the literature. We present the case of a 32-year-old patient who exhibited facial and oral swelling in the upper jaw.
View Article and Find Full Text PDFHuman T-lymphotropic Virus infection among Quilombo communities in Central Brazil.
Trans R Soc Trop Med Hyg
December 2024
Univer sidade Federal de Mato Grosso do Sul, Laboratório de Imunologia Clínica, Campo Grande 79070-900, Mato Grosso do Sul, Brazil.
Background: This study estimated the sociodemographic characteristics and prevalence of Human T-lymphotropic Virus (HTLV) infection among Afro-Brazilians in the two largest remnant Quilombo communities in Mato Grosso do Sul State.
Methods: Participants were interviewed from October 2015 to October 2016. Blood samples were collected and screened for anti-HTLV-1/2 antibodies using a commercial ELISA kit.
rs179008 (A/T) and rs3853839 (C/G) polymorphisms are associated with variations in IFN-α levels in HTLV-1 infection.
Front Immunol
December 2024
Laboratory of Virology, Institute of Biological Sciences, Federal University of Pará, Belém, Brazil.
Article Synopsis
- The study investigates how genetic variations in the TLR7 gene impact responses to HTLV-1 infection, focusing on cytokine production and disease symptoms.
- Researchers analyzed blood samples from HTLV-1 infected individuals, including those with inflammatory diseases and asymptomatic cases, alongside controls, using techniques like PCR and ELISA.
- Findings indicated that specific genetic variations (polymorphisms) affect levels of immune responses, with some variants linked to higher levels of antiviral activity, though they did not correlate with disease symptoms.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!