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Evaluating the pathological and clinical implications of errors made by an artificial intelligence colon biopsy screening tool.
BMJ Open Gastroenterol
January 2025
Histopathology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
Objective: Artificial intelligence (AI) tools for histological diagnosis offer great potential to healthcare, yet failure to understand their clinical context is delaying adoption. IGUANA (Interpretable Gland-Graphs using a Neural Aggregator) is an AI algorithm that can effectively classify colonic biopsies into normal versus abnormal categories, designed to automatically report normal cases. We performed a retrospective pathological and clinical review of the errors made by IGUANA.
View Article and Find Full Text PDFPerformance of Ulcer Features in Predicting Malignancy Among Gastric Ulcers Diagnosed on Upper Endoscopy.
J Clin Gastroenterol
December 2024
Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, TX.
Objective: Even though the prevalence of malignancy within gastric ulcers is low, surveillance endoscopy is routinely performed after gastric ulcer diagnosis resulting in unnecessary costs and risks. Endoscopic appearance may be used to identify ulcers with malignant features and guide decisions regarding the need for surveillance endoscopy. Our aim was to assess the predictive value of several endoscopic ulcer features with the risk of prevalent malignancy in patients diagnosed with gastric ulcers.
View Article and Find Full Text PDFSkin Tape Stripping Reveals Distinct Biomarker Profiles in Chronic Hand Eczema of Patients With and Without Comorbid Atopic Dermatitis.
Allergy
January 2025
Department of Dermatology, Icahn School of Medicine at the Mount Sinai, New York, New York, USA.
Introduction: Chronic hand eczema (CHE) is a highly prevalent inflammatory skin condition which is often resistant to conventional treatments. Molecular insights of CHE remain limited. Tape stripping combined with high-throughput RNA sequencing can now provide a better insight into CHE pathogenesis in a minimally invasive fashion.
View Article and Find Full Text PDFContinent catheterizable channels: Does "hitching" the bladder reduce complications?
J Pediatr Urol
December 2024
Division of Urology, Ann & Robert H. Lurie Children's Hospital of Chicago, 225 E Chicago Ave, Chicago, IL 60610, United States. Electronic address:
Background: Continent catheterizable channels (CCC) are a mainstay for reconstruction in patients with neurogenic bladders. Common complications include false passage, channel stenosis/difficult catheterization, channel incontinence, and stomal stenosis. This may result in the need for surgical revision or replacement.
View Article and Find Full Text PDFPolitical Orientation and Attitudes Toward Sexual Harassment: The Moderating Role of Gender.
J Interpers Violence
January 2025
University of the Balearic Islands (UIB), Palma de Mallorca, Spain.
Sexual harassment (SH) refers to unwelcome behavior that creates a hostile, intimidating, or offensive environment. This behavior can manifest through physical, verbal, or nonverbal actions. The present study analyzes the relationship between political orientation (left-wing, center, and right-wing) and attitudes toward SH with a focus on the moderating role of gender.
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