Background: Functional condition is crucial for operability of patients with lung cancer and/or chronic respiratory diseases. The aim of the study was to measure changes of functional and quality of life parameters in terms of the effectiveness of perioperative pulmonary rehabilitation (PR).

Methods: A total of 208 COPD patients (age: 63±9 years, man/woman: 114/94, FEV1: 62±14%pred) participated in a perioperative PR program. The indication was primary lung cancer in 72% of the patients. The 68 patients participated in preoperative (PRE) rehabilitation, 72 in a pre- and postoperative rehabilitation (PPO) and 68 patients only in postoperative rehabilitation (POS). PR program included respiratory training techniques, individualized training and smoking cessation. Lung function tests, 6 minutes walking distance (6MWD) were measured before and after the rehabilitation. Quality of life tests [COPD Assessment Test (CAT) and Modified Medical Research Council Dyspnoea Scale (mMRC)] were evaluated as well.

Results: There was a significant improvement in FEV1 (PRE: 64±16 67±16%pred; PPO: 60±13 66±13%pred before the operation, 48±13 52±13%pred after the operation; POS: 56±16 61±14%pred, P<0.05) and 6MWD (PRE: 403±87 452±86 m; PPO: 388±86 439±83 m before, 337±111 397±105 m after the operation; POS: 362±89 434±94 m, P<0 0001). Significant improvement was detected in FVC, grip strength, mMRC and CAT questionnaires as an effectiveness of PR, also. Average intensive care duration was 3.8±5.2 days with 3.1±3.6 without preoperative PR.

Conclusions: Improvements in exercise capacity and quality of life were seen following PR both before and after thoracic surgery.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506174PMC
http://dx.doi.org/10.21037/jtd.2017.05.49DOI Listing

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