Over the last decade there has been an explosion in the reactivity and applications of frustrated Lewis pair (FLP) chemistry. Despite this, the Lewis acids (LAs) in these transformations are often boranes, with heavier -block elements receiving surprisingly little attention. The novel LA BnSnOTf () has been synthesized from simple, inexpensive starting materials and has been spectroscopically and structurally characterized. Subtle modulation of the electronics at the tin centre has led to an increase in its Lewis acidity in comparison with previously reported RSnOTf LAs, and has facilitated low temperature hydrogen activation and imine hydrogenation. Deactivation pathways of the RSn LA core have also been investigated.This article is part of the themed issue 'Frustrated Lewis pair chemistry'.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540841 | PMC |
| http://dx.doi.org/10.1098/rsta.2017.0008 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Enhancing the Solubility of Co-Formulated Hydrophobic Drugs by Incorporating Functionalized Nano-Structured Poly Lactic--glycolic Acid (PLGA) During Co-Precipitation.
Pharmaceutics
January 2025
Department of Chemistry and Environmental Science, New Jersey Institute of Technology, Newark, NJ 07102, USA.
: The co-formulation of active pharmaceutical ingredients (APIs) is a growing strategy in biopharmaceutical development, particularly when it comes to improving solubility and bioavailability. This study explores a co-precipitation method to prepare co-formulated crystals of griseofulvin (GF) and dexamethasone (DXM), utilizing nanostructured, functionalized polylactic glycolic acid (PLGA) as a solubility enhancer. : An antisolvent precipitation technique was employed to incorporate PLGA at a 3% concentration into the co-formulated GF and DXM, referred to as DXM-GF-PLGA.
View Article and Find Full Text PDFPolyamines Interaction with Gaseous Signaling Molecules for Resilience Against Drought and Heat Stress in Plants.
Plants (Basel)
January 2025
Department of Botany, Aligarh Muslim University, Aligarh 202002, India.
Plants face a range of environmental stresses, such as heat and drought, that significantly reduce their growth, development, and yield. Plants have developed complex signaling networks to regulate physiological processes and improve their ability to withstand stress. The key regulators of plant stress responses include polyamines (PAs) and gaseous signaling molecules (GSM), such as hydrogen sulfide (HS), nitric oxide (NO), methane (CH), carbon monoxide (CO), carbon dioxide (CO), and ethylene (ET).
View Article and Find Full Text PDFProduction of Malheuran A, a Geranylated Flavonoid with Antimicrobial and Anti-Inflammatory Activities, in Hairy Root Cultures of .
Plants (Basel)
January 2025
Arkansas Biosciences Institute, Arkansas State University, Jonesboro, AR 72401, USA.
Phenolic compounds, such as stilbenes and flavonoids, from spp. exhibit diverse biological activities, including antimicrobial, anti-inflammatory, and cytotoxicity properties. To this end, the objectives of this study were to establish hairy root cultures of and assess its capacity to produce these bioactive compounds.
View Article and Find Full Text PDFTrade-Off Between Enzymatic Antioxidant Defense and Accumulation of Organic Metabolite Affects Salt Tolerance of White Clover Associated with Redox, Water, and Metabolic Homeostases.
Plants (Basel)
January 2025
Department of Turf Science and Engineering, College of Grassland Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
White clover () is an excellent perennial cold-season ground-cover plant for municipal landscaping and urban greening. It is, therefore, widely distributed and utilized throughout the world. However, poor salt tolerance greatly limits its promotion and application.
View Article and Find Full Text PDFPhytochemical Composition and Antioxidant Activity of Manuka Honey and Ohia Lehua Honey.
Nutrients
January 2025
Orthodontics, Department of Conservative Odontology, Faculty of Dental Medicine, "Iuliu Hațieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Unlabelled: Honey is abundant in bioactive compounds, which demonstrate considerable therapeutic effects, particularly on oxidative stress and inflammation.
Objectives: This work sought to evaluate the antioxidant mechanisms of Manuka honey (MH) and Ohia Lehua honey (OLH), correlating them with phytochemical analyses in a rat model of experimentally induced inflammation.
Methods: The identification of polyphenolic compounds in the extracts was carried out using HPLC-ESI MS.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!