Aims: To report the clinical outcome of infectious keratitis managed after doing 10% KOH mount of corneal smears and reporting done by an ophthalmologist in the secondary eye care centre in South India.
Methods: 103 consecutive cases of microbial keratitis were studied. Inclusion criteria were presence of corneal infiltrate on slit lamp biomicroscopy. An ophthalmologist carried out microbiological evaluation of 10% KOH mount of corneal scrapings. No cultures were done at secondary centres. Antifungal therapy with 5% Natamycin was initiated when 10% KOH mount was positive for fungal filaments. Else, the patients were started on combined topical ciprofloxacin (0.3%) and fortified cefazolin (5%).
Results: 41/103 (39.8%) smears were positive for fungus and 62 (60.2%) were negative. 89 out of 103 patients (86.40%) healed with scarring at an average of 2.95±1.58 weeks. Healing was noted in 39/41 (95.12%) of patients at an average of 3.06±1.19 weeks in patients with KOH smear positive keratitis. 80.64% (50/62) healed with scarring at an average period of 2.86±1.86 weeks in KOH mount negative keratitis.
Conclusions: Initial smear examination of KOH mount by an ophthalmologist helped in diagnosis of infectious keratitis caused by fungi and its management and 95.12% of KOH positive patients healed with scarring. Reading of KOH mount by an ophthalmologist helped in initiation of specific therapy with improved clinical outcome.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1136/bjophthalmol-2017-310241 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Clinico-Mycological Study of Dermatophytosis among Diabetic and Non-Diabetic Patients in a Tertiary Level Hospital: A Comparative Study.
Indian J Dermatol
October 2024
Department of Microbiology, JSS Medical College and Hospital, JSS Academy of Higher Education (Deemed to be University), Mysuru, Karnataka, India.
Background: Dermatophytosis is a major public health concern in India, especially in recent years, with an alarmingly rising trend, particularly in relation to recurrent and chronic infection. The number of studies examining the relationship between an individual's glycemic status and the development of dermatophytosis, and a comparison of the evolving species trend between diabetic and non-diabetic patients infected with dermatophytes, is limited.
Aims And Objectives: To study and compare the clinical and mycological aspects of dermatophytosis among diabetic and non-diabetic patients and to compare the culture isolates in both groups.
Updated consensus guidelines for management of moderate-to-severe atopic dermatitis in Singapore: Integrating biologics, Janus kinase inhibitors and conventional therapies.
Ann Acad Med Singap
November 2024
Department of Dermatology, Singapore General Hospital, Singapore.
Article Synopsis
- Several new therapies, including biologics and JAK inhibitors, have been approved for treating atopic dermatitis (AD) in Singapore since 2016, leading to an update of treatment guidelines for moderate-to-severe cases.
- A modified Delphi panel with 12 dermatologists conducted surveys to reach consensus on treatment statements, resulting in agreement on 43 statements across different treatment categories.
- The study highlights dupilumab and JAK inhibitors as potential first-line treatments for certain patients with moderate-to-severe AD, and indicates that further updates to the guidelines may be necessary as new information emerges.
THE CLINICAL MANIFESTATIONS OF SCABIES IN PATIENTS PRESENTING TO DERMATOLOGY OUTPATIENTS DEPARTMENT AT AYUB TEACHING HOSPITAL, ABBOTTABAD.
J Ayub Med Coll Abbottabad
November 2024
Department of Dermatology, Ayub Medical College, Abbottabad-Pakistan.
Background: Scabies is a significant skin problem in the developing countries due to its increased incidence, complications and financial implications. The aim of this study is to highlight the endemicity of scabies in our population and its clinical manifestations including various complications. The study was conducted to determine the frequency and clinical manifestations of scabies in patients presented to dermatology outpatient department (opd), Ayub teaching hospital, Abbottabad.
View Article and Find Full Text PDFSIADH secondary to rhino-orbito-cerebral mucormycosis: A case report.
Clin Case Rep
November 2024
Institute of Medicine Maharajgunj Medical Campus, Tribhuvan University Kathmandu Nepal.
Key Clinical Message: Invasive fungal mucormycosis and its outcome as SIADH and orbital apex syndrome is uncommon. Mucormycosis in paranasal sinuses can even lead to intracranial invasion and its treatment with the use of amphotericin B can cure improve the prognosis of the disease. Early diagnosis and prompt treatment with antifungal, endoscopic surgery, and controlling of diabetes can be beneficial.
View Article and Find Full Text PDFSelf-assembled sub-picoliter liquid periodic structures in a hollow optical fiber.
Sci Rep
October 2024
Institute of Physics and Applied Physics, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
In an experimental exploration, we successfully implemented a self-assembling methodology to construct a periodic liquid-air structure inside a hollow optical fiber (HOF). This fiber comprises a central air hole, a germanosilica ring core, and a silica cladding. A periodic structure of liquid droplets and air was obtained by the application of a microscopic heat source (MHS) traversing along the axial direction of the liquid-filled HOF.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!