AI Article Synopsis
- The study aimed to determine the prevalence of extended-spectrum beta-lactamases (ESBL) in Enterobacteriaceae causing hospital infections and to analyze the phylogenetic groups in E. coli isolates.
- Researchers collected 1,084 ESBL-producing Enterobacteriaceae isolates from adult patients across multiple hospitals in Mexico from 2005 to 2012, testing for various ESBL genes.
- Results showed that E. coli and Klebsiella pneumoniae were the most frequent isolates, with CTX-M-type ESBLs being the most common, especially CTX-M-15, indicating a shift in bacterial species prevalence in hospital settings in Mexico.
Article Abstract
Objectives: To identify the prevalence of ESBL genes in the principal group of Enterobacteriaceae causing nosocomial infections and to identify the phylogenetic group in Escherichia coli isolates.
Methods: There were collected 1084 ESBL-producing Enterobacteriaceae isolates during 2005-2012 from adult patients from 14 hospitals and corresponding to eight states and five regions (SE, S, N, W and NW) in Mexico. The CTX-M-(CTX-M-1 group), SHV-, TLA- and GES-type ESBLs genes were screened. The respective alleles were determined in the most of ESBLs genes. In E. coli isolates selected were used to identify the phylogenetic group.
Results: The ESBL-producing Escherichia coli and Klebsiella pneumoniae corresponded the most prevalent clinical isolates. CTX-M-type ESBLs genes were the most common, followed by SHV-type, GES-type and the ESBLs TLA-1 gene. The allelic frequency showed to CTX-M-15 ESBL the most prevalent, followed by the SHV-12, SHV-5 and GES-1, GES-19 in the GES family. Among ESBL-producing E. coli isolates the phylogenetic groups A and D were the most common ones.
Conclusions: The present study showed an epidemiological change in terms of bacterial species, placing E. coli as the most frequently isolated bacteria among ESBL-producing Enterobacteriaceae in Mexico, followed by K. pneumoniae. This frequency is accompanied by a high frequency of ESBL CTX-M-15.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jgar.2017.06.008 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Dual-Stage Cross-Flow Filtration: Integrated Capture and Purification of Virus-Like Particles.
Biotechnol Bioeng
December 2024
Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
Virus-like particles (VLPs) are a versatile technology for the targeted delivery of genetic material through packaging and potential surface modifications for directed delivery or immunological issues. Although VLP production is relatively simple as they can be recombinantly produced using microorganisms such as Escherichia coli, their current downstream processing often relies on individually developed purification strategies. Integrating size-selective separation techniques may allow standardized platform processing across VLP purification.
View Article and Find Full Text PDFPantoea dispersa Causing Bacteremia and Endocarditis in an Immunocompromised Adult: A Rare Case.
Cureus
November 2024
Department of Internal Medicine, University of Missouri Kansas City School of Medicine, Kansas City, USA.
Gram-negative rods, namely, and , are the most common causative agents of bacteremia. The genus , another group of Gram-negative rods, is a relatively uncommon cause of bacteremia. Our literature review revealed only eight other cases of infection in humans.
View Article and Find Full Text PDFDiagnostic and Therapeutic Value of Endoscopic Retrograde Cholangiopancreatography in Acute Cholangitis: A Study From Kashmir Valley, India.
Cureus
November 2024
Radiation Oncology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, IND.
Background Cholangitis, or bile duct infection, can present in two primary forms, namely, acute ascending cholangitis (the milder form) and acute fulminant cholangitis (the more severe variety). In all types of cholangitis, bile duct obstruction occurs, with choledocholithiasis (the presence of gallstones in the bile duct) being the leading cause of this blockage. is the most commonly isolated pathogen in these infections.
View Article and Find Full Text PDFA simple predictive model for puerperal infections: emphasizing risk factors and pathogen analysis.
Front Cell Infect Microbiol
December 2024
Department of Obstetrics and Gynecology, Women and Children's Hospital of Chongqing Medical University, Chongqing, China.
Background: Puerperal infection (PI) accounting for approximately 11% of maternal deaths globally is an important preventable cause of maternal morbidity and mortality. This study aims to analyze the high-risk factors and pathogenic bacteria of PI, design a nomogram to predict the risk of PI occurrence, and provide clinical guidance for prevention and treatment to improve maternal outcomes.
Methods: A total of 525 pregnant women were included in the study.
Bacteriological load in Holstein Friesian cows with dystocia.
Front Vet Sci
December 2024
Department Clinics, Reproduction, Faculty of Veterinary Medicine, University of Life Sciences (IULS), Iași, Romania.
The research took place on a farm in North-Eastern Romania with Holstein Friesian cows aged between 3 and 9 years. Bacteriological investigations were carried out throughout the year 2023, on a total of 35 cows, including 25 multiparous cows and 10 primiparous cows, 23 cows had eutocic parturitions and 12 cows had dystocic parturitions, during the first 3 weeks postpartum. In the case of dystocic parturition, biological samples yielded isolates including 9.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!