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Urinary Vacuolar Casts Are a Unique Type of Casts in Advanced Proteinuric Glomerulopathies.
Kidney360
February 2024
Department of Nephrology, Ochsner Health, New Orleans, Louisiana.
Key Points: Vacuolar casts are a distinct type of casts identifiable by urinary sediment microscopy. Identification of urinary vacuolar casts is associated with the presence of an advanced and severe form of a proteinuric glomerular disease.
Background: Identification of casts by urinary sediment microscopy is a valuable diagnostic clinical tool for the evaluation of kidney disease.
AJKD Atlas of Renal Pathology: IgA-Dominant Infection-Related Glomerulonephritis.
Am J Kidney Dis
January 2024
Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, Tennessee. Electronic address:
Precision Medicine in Nephrology: An Integrative Framework of Multidimensional Data in the Kidney Precision Medicine Project.
Am J Kidney Dis
March 2024
Kidney Research Institute and Division of Nephrology, University of Washington, Seattle, Washington. Electronic address:
Chronic kidney disease (CKD) and acute kidney injury (AKI) are heterogeneous syndromes defined clinically by serial measures of kidney function. Each condition possesses strong histopathologic associations, including glomerular obsolescence or acute tubular necrosis, respectively. Despite such characterization, there remains wide variation in patient outcomes and treatment responses.
View Article and Find Full Text PDFApproach to Kidney Biopsy: Core Curriculum 2022.
Am J Kidney Dis
July 2022
Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address:
The kidney biopsy is an essential tool for diagnosis of many kidney diseases. Obtaining an adequate biopsy sample with appropriate allocation for various studies is essential. Nephrologists should understand key lesions and their interpretation because these are essential elements underlying optimal approaches for interventions.
View Article and Find Full Text PDFKidney Disease, Hypertension Treatment, and Cerebral Perfusion and Structure.
Am J Kidney Dis
May 2022
Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Rationale & Objective: The safety of intensive blood pressure (BP) targets is controversial for persons with chronic kidney disease (CKD). We studied the effects of hypertension treatment on cerebral perfusion and structure in individuals with and without CKD.
Study Design: Neuroimaging substudy of a randomized trial.
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