Utility of a laboratory score in the prediction of gastric emptying in autoimmune gastritis patients.

Acta Clin Belg

a Departments of Internal Medicine, Gastroenterology , Ankara University Faculty of Medicine, Ankara , Turkey.

Published: February 2018

AI Article Synopsis

  • The study investigates how two scoring systems can help differentiate between delayed and normal gastric emptying in patients with autoimmune gastritis.
  • Results show that both the 'simple score' and 'global score' significantly differ between patients with delayed gastric emptying and those with normal gastric emptying, indicating their predictive value.
  • The findings suggest that these scoring systems can assist healthcare providers in deciding when to conduct gastric emptying tests for patients with autoimmune gastritis.

Article Abstract

Objectives: Patients with autoimmune gastritis may have symptoms suggestive of delayed gastric emptying. The aim of this study was to explore the predictive value of two scoring systems in the differentiation of delayed gastric emptying in patients with autoimmune gastritis.

Methods: About 154 patients (106 women) with autoimmune gastritis whose gastric emptying test were available, were analyzed using two laboratory-based scoring systems: 'global score' (hemoglobin, mean corpuscular volume, gastrin, vitamin B, and chromogranin A) and 'simple score' (hemoglobin, mean corpuscular volume, and gastrin) in order to discriminate delayed and normal gastric emptying.

Results: The mean 'simple score' was 4.82 ± 0.94 for autoimmune gastritis patients with delayed gastric emptying and 0.72 ± 0.60 for patients with normal gastric emptying (p < 0.001). The mean 'global score' was 7.42 ± 0.81 for autoimmune gastritis patients with delayed gastric emptying and 1.176 ± 0.98 (p < 0.001) for patients with normal gastric emptying. There was also a positive correlation between severity of symptoms of patients with autoimmune gastritis and global (r = 0.83, p < 0.001) and simple scores (r = 0.81, p < 0.001).

Conclusion: This model may help physicians, while evaluating autoimmune gastritis patients and deciding which patients need gastric emptying test. Gastric emptying study should be ordered in patients who are fulfilling the criteria proposed by these scoring systems.

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Source
http://dx.doi.org/10.1080/17843286.2017.1353773DOI Listing

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