AI Article Synopsis
- Human caliciviruses, especially norovirus genotype GII.4, are significant causes of viral diarrhea in children, as highlighted by a study in China.
- Among 295 children with acute diarrhea, 10.85% tested positive for HuCV, with most being HBGA secretors or partial secretors, while only a small percentage of asymptomatic children tested positive.
- The findings suggest that blood type O may be linked to a higher risk of GII.3 infection, but due to the small sample size, additional research is needed for confirmation.
Article Abstract
Human caliciviruses (HuCVs) have been recognized as a major cause of sporadic viral diarrhea in children, among which norovirus genotype GII.4 is the most prevalent genotype. Stool and saliva samples were collected from 295 children with acute diarrhea and 150 asymptomatic children at a hospital in China. The HuCV detection rate was 10.85% (32/295) among the children with acute diarrhea, and all of these 32 children were either HBGA secretors (12/32) or partial secretors (20/32). HuCV was detected in two (1.33%) of the 150 samples obtained from the asymptomatic children. Of the norovirus-GII.3-positive children, 60% had blood type O, but only 17.29% of the symptomatic patients had blood type O, indicating that type O individuals could be at higher risk of GII.3 infection. However, due to the limited number of individuals in this study, further studies with a larger number of subjects should be conducted to verify this hypothesis.
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| http://dx.doi.org/10.1007/s00705-017-3494-y | DOI Listing |
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