In this paper a new methodology to detect and differentiate melanoma cells from normal cells through 1D-signatures averaged variances calculated with a binary mask is presented. The sample images were obtained from histological sections of mice melanoma tumor of 4 [Formula: see text] in thickness and contrasted with normal cells. The results show that melanoma cells present a well-defined range of averaged variances values obtained from the signatures in the four conditions used.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516832 | PMC |
| http://dx.doi.org/10.1364/BOE.8.002185 | DOI Listing |
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