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Current Practice and Outcomes of Patients Undergoing Surgical Resection for Renal Cell Metastases to the Pancreas in Northern Ireland.
Ulster Med J
December 2024
Department of Hepatobiliary and Pancreatic Surgery, Belfast Health and Social Care Trust, Belfast, UK.
Article Synopsis
- * A study reviewed 15 patients who had pancreatic surgery for metastatic RCC over 18 years, finding that most had isolated pancreatic metastases and a long disease-free interval from their initial kidney tumor.
- * Five-year survival rates post-surgery were 32.7% for disease-free survival and 63.3% for overall survival, with specific factors like synchronous cancer leading to shorter survival outcomes, while a longer gap before metastasis was associated with better overall survival trends.
The Emerging Role of Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Pancreatic Cancer.
J Surg Oncol
November 2024
Division of Hepatobiliary and Pancreas Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Article Synopsis
- Peritoneal spread often leads to metastasis in patients with pancreatic cancer, occurring both at the same time and at different times as the disease progresses.
- Advances in systemic chemotherapy for pancreatic cancer have improved treatment options for patients.
- Careful patient selection could allow those with limited metastasis in the peritoneum to benefit from consolidative surgery and HIPEC (Hyperthermic Intraperitoneal Chemotherapy).
Posterior retroperitoneal adrenalectomy for metastatic disease: a multi-site Australian series.
ANZ J Surg
November 2024
Surgical Services, John Hunter Hospital, New Lambton Heights, New South Wales, Australia.
Background: Posterior retroperitoneoscopic adrenalectomy (PRA) for isolated adrenal metastasis is minimally invasive, may prolong survival and improve quality of life. The current evidence base is scant.
Methods: A multi-site retrospective analysis of all cases of PRA for adrenal metastasis between 2011 and 2023, by four high-volume adrenal surgeons was performed.
Surgical Management of Genitourinary Cancer Liver Metastases.
Hematol Oncol Clin North Am
February 2025
Division of Medical Oncology, Department of Medicine, The Ottawa Hospital, University of Ottawa, 501 Smyth Road, Ottawa, Ontario K1H 8L6, Canada.
Genitourinary cancers are common. Liver metastases from genitourinary cancers are uncommon; isolated liver metastasis is rare. Liver resection in select patients with metastatic renal cell carcinoma can lead to prolonged survival.
View Article and Find Full Text PDFHepatic Perfusion for Diffuse Metastatic Cancer to the Liver: Open and Percutaneous Techniques.
Hematol Oncol Clin North Am
February 2025
Division of Surgical Oncology, Rutgers Cancer Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
The management of patients with diffuse liver metastases remains a significant clinical challenge. In many cancer patients, metastatic disease may be isolated to the liver or the liver may be the dominant site of progressive metastatic cancer. In this setting, progression of disease in the liver generally is the most significant cause of morbidity and mortality.
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