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FRAX Update. | LitMetric

FRAX Update.

J Clin Densitom

Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Sheffield, UK.

Published: June 2018

AI Article Synopsis

Article Abstract

The fracture risk assessment tool, FRAX, was released in 2008 and provides country-specific algorithms for estimating individualized 10-year probability of hip and major osteoporotic fracture (hip, clinical spine, distal forearm, and proximal humerus). Since its release, models are now available for 63 countries, covering 79% of the world population. The website receives approximately 3 million visits annually. Following independent validation, FRAX has been incorporated into more than 80 guidelines worldwide. However, the application of FRAX in guidelines has been heterogeneous with the adoption of several different approaches to setting intervention thresholds. The relationship between FRAX and efficacy of intervention has been explored and is expected to influence treatment guidelines in the future. A more unified approach to setting intervention thresholds with FRAX is a research priority.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jocd.2017.06.022DOI Listing

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