AI Article Synopsis
- Invasive fungal infections are uncommon in children with acute lymphoblastic leukemia but can jeopardize treatment and have a high mortality rate if they affect the central nervous system.
- A case is presented of a 6.5-year-old girl who developed multiple central nervous system fungal abscesses, likely from Aspergillus, during her leukemia treatment, yet she successfully continued her antileukemia therapy.
- The girl has been on antifungal treatment and maintenance chemotherapy for 20 months, and the authors reviewed existing literature on the treatment duration, which varies from 4 to 24 months for similar cases.
Article Abstract
Invasive fungal infections are rare in children with acute lymphoblastic leukemia. It compromises the antileukemia therapy should it happen. Central nervous system fungal infections carry high mortality. We here report the case of a 6.5-year-old girl who developed multiple central nervous system fungal abscesses possibly due to Aspergillus infection during induction therapy for acute lymphoblastic leukemia who has been successfully managed without compromising antileukemia therapy. She has been receiving antifungal therapy and maintenance chemotherapy for 20 months from diagnosis. We reviewed literature about the optimal duration of therapy for such children as the reported cases duration ranged between 4 and 24 months.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/MPH.0000000000000855 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!