Objective: To explore the clinical application of the intracavitary electrocardiogram (IC-ECG) guided Peripherally Inserted Central Catheter (PICC) tip placement among neonates.
Background: the ECGs of neonates are difficult to perform and their wave shapes are of doubtful accuracy due to various interfering factors.
Method: 115 neonates were admitted to perform PICC guided by IC-ECG. Logistic regression was performed to analyze all possible influencing factors of the accuracy from the tip placement. The puncture site of the PICC, gestational age, height, weight, basal P/R amplitude and positioning P/R amplitude might be related to the accuracy of IC-ECG location.
Result: The accuracy in the lower extremity was higher than that in the upper extremity. Multivariate logistic regression analysis showed that the weight (Odds Ratio (OR)=1.93, 95%Confidence Interval(CI):1.06-3.50) and positioning P/R amplitude (OR=32.33, 95%CI: 2.02-517.41) are statistically significant risks to the accuracy PICC tip placement.
Conclusions: Possible methods to improve the accuracy might be Catheterizing through lower extremity, keeping the neonates calm, enhancing the electrocardiogram signal and strengthening technical training. Therefore it is practical to perfrom a tip placement by the dynamic change in the P waves from an electrocardiogram (ECG) guided PICC among neonates and as reliable as using X-rays.
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http://dx.doi.org/10.1515/med-2017-0019 | DOI Listing |
Photodiagnosis Photodyn Ther
January 2025
Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, Zhejiang, 315000, P.R. China. Electronic address:
Purpose: To evaluate the differences in fundus tessellation among various severities using multifocal visual electrophysiology (MfERG) and optical coherence tomography angiography (OCTA) for clinical grading and treatment.
Methods: This study included 52 patients totaling 87 eyes. The Early Treatment Diabetic Retinopathy Study (ETDRS) grid division method was utilized to assess Grade of fundus tessellation.
Adv Sci (Weinh)
January 2025
Hebei Key Laboratory of Photo-Electricity Information and Materials, College of Physics Science and Technology, Hebei University, Baoding, 071002, P. R. China.
Metal halide perovskites (MHPs) are commonly used in polarization-sensitive photodetectors (PDs) for applications such as polarization imaging, remote sensing, and optical communication. Although various methods exist to adjust the polarization-sensitive photocurrent, a universal and effective approach for continuous control of MHPs' optoelectronic and polarized properties is lacking. A universal strategy to electrically modulate the polarization ratio (PR) of self-powered polarized PDs using the ferro-pyro-phototronic effect (FPPE) in 2D perovskites is presented.
View Article and Find Full Text PDFNanoscale
January 2025
School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100191, China.
Low-frequency noise in detection systems significantly affects the performance of ultrasensitive and ultracompact spin-exchange relaxation-free atomic magnetometers. High frequency modulation detection helps effectively suppress the 1/ noise and enhance the signal-to-noise ratio, but conventional modulators are bulky and restrict the development of integrated atomic magnetometer modulation-detection systems. Resonant metasurface-based thin-film lithium-niobate (TFLN) active optics can modulate free-space light within a compact configuration.
View Article and Find Full Text PDFActa Physiol (Oxf)
February 2025
Institute for Physiology, University Medical Centre of the Johannes Gutenberg University Mainz, Mainz, Germany.
Aim: Despite dysfunctional vasoactive intestinal polypeptide-positive interneurons (VIP-INs) being linked to the emergence of neurodevelopmental disorders, the temporal profile of VIP-IN functional maturation and cortical network integration remains unclear.
Methods: Postnatal VIP-IN development was traced with patch clamp experiments in the somatosensory cortex of Vip-IRES-cre x tdTomato mice. Age groups were chosen during barrel field formation, before and after activation of main sensory inputs, and in adult animals (postnatal days (P) P3-4, P8-10, P14-16, and P30-36).
Adv Sci (Weinh)
January 2025
State Key Laboratory for Manufacturing Systems Engineering, Xi'an Jiaotong University, Xi'an, 710049, P. R. China.
Micro/nanoscale 3D bioelectrodes gain increasing interest for electrophysiological recording of electroactive cells. Although 3D printing has shown promise to flexibly fabricate 3D bioelectronics compared with conventional microfabrication, relatively-low resolution limits the printed bioelectrode for high-quality signal monitoring. Here, a novel multi-material electrohydrodynamic printing (EHDP) strategy is proposed to fabricate bioelectronics with sub-microscale 3D gold pillars for in vitro electrophysiological recordings.
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