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Image Guidance is Associated with Improved Freedom From Recurrence After Superficial Radiation Therapy for Nonmelanoma Skin Cancer.
Adv Radiat Oncol
December 2024
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio.
Purpose: This is the first study to quantify the 2-year freedom from recurrence for individuals with nonmelanoma skin cancer (NMSC) such as basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and squamous carcinoma in situ (SCCIS) treated with image guided superficial radiation therapy (IGSRT) versus SRT without image guidance.
Methods And Materials: This retrospective cohort study evaluates the 2-year freedom recurrence rate of NMSCs treated by IGSRT (March 2016 to January 2022) and compares it to existing data on NMSCs treated by SRT via 1 sample proportion tests. Individuals >18 years old with biopsy-proven SCC, SCCIS, and/or BCC treated with IGSRT were included in the study, and 1602 patients/2880 treated lesions were followed until January 14, 2022.
Local flap guidance for scalp reconstruction following Mohs micrographic surgery.
Arch Dermatol Res
January 2025
Department of Dermatology, University of Texas Medical Branch, 301 University Boulevard, 4.112, McCullough Building, Galveston, TX, 77555, USA.
Keratinocyte carcinomas (KCs) are commonly located on the scalp and often treated with excision with peripheral and deep en face margin assessment (PDEMA), with Mohs micrographic surgery (MMS) being the most frequently used method. Resection of these malignancies results in wounds with a wide variety of sizes, ranging from small, sub-centimeter defects, to extensive, nearly complete scalp defects. MMS is often the preferred treatment for tumor resection and margin clearance, as it allows for maximal healthy tissue preservation and has the lowest recurrence rates.
View Article and Find Full Text PDFCorrigendum to "Image-guided superficial radiation therapy has superior 2-year recurrence probability to Mohs micrographic surgery" [Clin. Transl. Radiat. Oncol. 43 (2023) 100678].
Clin Transl Radiat Oncol
January 2025
Cleveland Clinic, Dept of Quantitative Health Sciences, Mail Code JJN3, 9500 Euclid Avenue, Cleveland, OH 44195, United States.
[This corrects the article DOI: 10.1016/j.ctro.
View Article and Find Full Text PDFBackground: Nasal defects after skin cancer excision can often be healed by second intention in certain circumstances.
Objective: We aim to demonstrate the utility of bovine collagen xenografts in supplementing second-intention healing of a variety of nose surgical defects.
Results: Thirty-nine patients underwent Mohs micrographic surgery of the nasal tip (33%), ala (23%), dorsum (31%), sidewall (10%), and root (3%) with the application of bovine collagen xenograft.
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