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Development of Amniotic Epithelial Stem Cells Secretome-Loaded Inverse Electron Demand Diels-Alder-Cross-Linked Hydrogel as a Potential Immunomodulatory Therapeutical Tool.
ACS Appl Mater Interfaces
January 2025
Drug Research Program, Division of Pharmaceutical Chemistry and Technology, University of Helsinki, 00014 Helsinki, Finland.
Article Synopsis
- Amniotic epithelial stem cells (AEC) have regenerative potential, particularly through their conditioned medium (AEC-CM), which shows immunomodulatory and regenerative effects.
- A novel hydrogel made from hyaluronic acid and polyethylene glycol was developed to encapsulate AEC-CM, with features like fast cross-linking and sustained growth factor release over 14 days.
- Studies demonstrate that the encapsulated AEC-CM significantly enhances the suppression of peripheral blood mononuclear cells and promotes a shift towards the beneficial M2 macrophage phenotype, suggesting its viability as an immunomodulatory treatment for tissue regeneration.
Freud's interpretation in "Medusa's Head" and some alternative psychoanalytic implications of Ovid's Medusa.
Int J Psychoanal
April 2024
Professor Emeritus, The University of London, London, UK.
Freud's very brief 1922 paper on the beheading of Medusa by Perseus wisely concludes with a call for a further examination of the sources of the legend. A now widespread interpretation of this legend is based (often without acknowledgement) on an addition to traditions concerning Medusa made in Ovid's . It is argued here that this Ovidian innovation has often been misinterpreted, and that a more careful reading of supports neither a widely alleged exclusively vengeful portrayal of Medusa, nor Freud's portrayal of Medusa's decapitation as a pitiable and terrible symbol of castration.
View Article and Find Full Text PDFWhere myth and archaeology meet: Discovering the Gorgon Medusa's Lair.
PLoS One
September 2021
Department of Earth Sciences and CIPHCN-Heritage Centre, University of Huelva, Huelva, Spain.
Here we report the discovery of ceramic fragments that form part of a Gorgoneion, a ceramic image representation of the Gorgon Medusa. The fragments were found in a deep part of Gorham's Cave, well known to ancient mariners as a natural shrine, between the 8th and 2nd century BCE. We discuss the context of this discovery, both within the inner topography of the cave itself, and also the broader geographical context.
View Article and Find Full Text PDFThe legend of Medusa with snake hair in Didymaion, in Didyma, Turkey.
Childs Nerv Syst
December 2018
Department of Neurosurgery, Adnan Menderes University School of Medicine, 09100, Aydın, Turkey.
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