The Yes‐associated protein (YAP) is an important transcriptional co‐activator that mediates the cellular response to mechanical and cytoskeletal cues. In two recent papers published in , Dae‐Sik Lim and colleagues show how YAP activity affects cancer formation and metastasis via a crosstalk with myocardin‐related transcription factors (MRTFs; Kim , 2017) and SKP2‐dependent cell cycle progression (Jang , 2017).
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579380 | PMC |
| http://dx.doi.org/10.15252/embj.201797527 | DOI Listing |
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