AI Article Synopsis
- A study examined the relationship between serum hemoglobin (HGB) and hematocrit (HCT) levels with the attenuation values of blood vessels in noncontrast-enhanced CT scans, potentially affecting CT perfusion maps.
- Researchers analyzed data from 45 patients with acute neurological symptoms who underwent both NECT and CT perfusion scans, alongside follow-up MRI.
- The findings indicated no difference in HCT and HGB between stroke patients and controls, but revealed a significant correlation between HCT, HGB, and attenuation values in certain arteries; however, these factors did not impact perfusion maps or necessitate adjustments for cerebral blood volume thresholds in stroke patients.
Article Abstract
Objective: There is a correlation between both serum hemoglobin (HGB) and hematocrit (HCT) and attenuation values of vessels in noncontrast-enhanced computed tomography (NECT), which could influence calculated perfusion maps in CT perfusion.
Methods: We retrospectively included 45 patients, who presented with acute new neurological symptoms and underwent NECT and CT perfusion (128-row multi detector scanner, coverage: 6.9 cm craniocaudally; 80 kV; 200 mAs; temporal resolution: 2 seconds using 40 mL Ultravist 370 at a flow rate of 5 mL/s) on admission and a follow-up MRI within 1 week of admission.
Results: Hematocrit, HGB, and attenuation values did not differ between patients with stroke and controls. A statistically significant correlation was found between HCT and HGB and attenuation values in the internal carotid artery or middle cerebral artery on NECT (P < 0.05). No statistically significant correlation was observed between HCT and HGB and perfusion maps.
Conclusions: Hematocrit and HGB do not influence calculated perfusion maps. There is no need for HCT/HGB-adjusted cerebral blood volume thresholds in stroke patients.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/RCT.0000000000000560 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Association of Physical Function, Quantity, and Quality of the Quadriceps with Postoperative Physical Activity Before Total Knee Arthroplasty.
J Clin Med
January 2025
Department of Orthopedic Surgery, Graduate School of Medicine Sciences, Kanazawa University, 13-1 Takaranachi, Kanazawa 920-8641, Ishikawa, Japan.
This single-center cohort study investigated preoperative risk factors such as physical function, quantity, and quality of the quadriceps femoris for physical activity (PA) 1 year after total knee arthroplasty (TKA). This study included 204 patients with knee osteoarthritis who underwent TKA; they were divided into increased and decreased PA groups. Items with significant differences between the two groups in non-operative-side quadriceps strength, knee injury and osteoarthritis outcome scores (KOOS), Sport/Rec scores, operative-side cross-sectional area (CSA) of the vastus medialis (VM), and operative-side computed tomography attenuation values (CTV) of the vastus lateralis (VL) were fitted in the multiple logistic regression analysis.
View Article and Find Full Text PDFDiffuse Noxious Inhibitory Controls in Chronic Pain States: Insights from Pre-Clinical Studies.
Int J Mol Sci
January 2025
Instituto de Investigação e Inovação em Saúde da Universidade do Porto-i3S, R. Alfredo Allen 208, 4200-135 Porto, Portugal.
Diffuse noxious inhibitory control (DNIC), also known as conditioned pain modulation (CPM) in humans, is a paradigm wherein the heterotopic application of a noxious stimulus results in the attenuation of another spatially distant noxious input. The pre-clinical and clinical studies show the involvement of several neurochemical systems in DNIC/CPM and point to a major contribution of the noradrenergic, serotonergic, and opioidergic systems. Here, we thoroughly review the latest data on the monoaminergic and opioidergic studies, focusing particularly on pre-clinical models of chronic pain.
View Article and Find Full Text PDFAssociation Between Lung Parenchymal Attenuation in Computed Tomography and Airflow Limitation in Adults with Cystic Fibrosis.
Diagnostics (Basel)
January 2025
Servicio de Neumología, Hospital Universitario La Paz, IdiPAZ, CIBERES, Universidad Autónoma de Madrid, 28046 Madrid, Spain.
: To determine the association between airflow limitation and the quantification of lung attenuation in computed tomography (CT) in adult patients with cystic fibrosis (CF). : A cross-sectional study in a single center between January 2013 and December 2018 in adult patients with stable CF. We collected clinical data and the results of spirometry and plethysmography.
View Article and Find Full Text PDFScots Pine Bark Extracts as Co-Hardeners of Epoxy Resins.
Molecules
December 2024
Department of Physical Chemistry, Faculty of Chemistry, University of Łódź, Pomorska 163/165, 90-236 Łódź, Poland.
Extracts from natural waste like bark or leaves are great sources of phytochemicals, which contain functional groups (hydroxyl, carboxylic, vinyl, allyl) attractive in terms of polymer synthesis. In this study, the synthesis of epoxy with an extract of Scots pine bark as a natural co-hardener was evaluated. Ultraviolet-visible (UV-Vis) spectroscopy was used for the identification of phytochemicals with conjugated dienes and quantification of TPC.
View Article and Find Full Text PDFGasoline exhaust particles induce MMP1 expression via Nox4-derived ROS-ATF3-linked pathway in human umbilical vein endothelial cells.
Toxicology
January 2025
Division of Cardiovascular Disease Research, Department of Chronic Disease Convergence Research, Korea National Institute of Health, Cheongju, Republic of Korea.
Gasoline exhaust particles (GEP) are risk factors for cardiovascular disease. Activating transcription factor 3 (ATF3) is a transcription factor known to form a heterodimer with AP-1 transcription factors for its target gene expression. However, the involvement of ATF3 in GEP-induced gene expression in human umbilical vein endothelial cells (HUVECs) has not been investigated.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!