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Background And Purpose: Pneumonia is the most important respiratory problem in low-to-middle income countries. Airway clearance therapy continues to be used in children with pneumonia and secretion retention; however, there is lack of evidence to support or reject this treatment. This study aimed to investigate the feasibility of a randomized controlled trial (RCT) on the efficacy and safety of assisted autogenic drainage (AAD) compared to standard nursing care in children hospitalized with uncomplicated pneumonia.
Methods: A single-blinded pilot RCT was conducted on 29 children (median age 3.5 months, IQR 1.5-9.4) hospitalized with uncomplicated pneumonia. The intervention group received standard nursing care with additional bi-daily AAD, for 10 to 30 min. The control group only received standard nursing care, unless otherwise deemed necessary by the physician or physiotherapist. The primary outcome measure was duration of hospitalization. The secondary outcome measures included days of fever and supplemental oxygen support; respiratory rate (RR) and heart rate adjusted for age; RR and oxygen saturation pre-, post-, and 1-hr post-treatment; oxygen saturation; adverse events; and mortality.
Results: No difference was found for duration of hospitalization (median 7.5 and 7.0 days for the control and intervention groups, respectively); however, Kaplan-Meier analysis revealed a strong tendency towards a shorter time to discharge in the intervention group (p = .06). No significant differences were found for the other outcome measures at time of discharge. No adverse events were reported. Within the intervention group, a significant reduction in RR adjusted for age was found.
Discussion: As no adverse events were reported, and AAD did not prolong hospitalization; AAD might be considered as safe and effective in young children with uncomplicated pneumonia. However, a larger multicentred RCT is warranted to determine the efficacy of AAD compared to standard nursing care.
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http://dx.doi.org/10.1002/pri.1690 | DOI Listing |
Risk Manag Healthc Policy
December 2024
Nursing College, Taibah University, Madinah, Saudi Arabia.
Purpose: This study investigated the daily practices of community nurses working in Primary Health Care Centers (PHCCs) and their learning needs.
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Front Pharmacol
December 2024
Faculty of General Medicine, Yaroslavl State Medical University, Yaroslavl, Russia.
Background And Objective: Dental implant therapy faces challenges in patients with Type 1 and Type 2 Diabetes Mellitus (T1DM and T2DM) due to adverse effects on bone metabolism and immune response. Despite advancements, diabetic patients face higher risks of peri-implantitis and compromised osseointegration. This review assesses the impact of anti-diabetic medications on implant outcomes, offering insights to bridge the gap between animal studies and clinical practice.
View Article and Find Full Text PDFJ Family Med Prim Care
November 2024
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View Article and Find Full Text PDFBMC Med Educ
December 2024
Shanxi Provincial People's Hospital, No. 29 Shuangta East Street, Yingze District, Taiyuan City, Shanxi Province, China.
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Prehosp Disaster Med
December 2024
School of Nursing & Midwifery, The University of Newcastle, New South Wales, Australia.
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