Objectives: To investigate the clinical course of fetal tachycardia and analyze the impact of intrauterine treatment on the postnatal treatment and patient outcomes.
Study Design: This was a retrospective review of cases of fetal tachycardia that occurred from 2004 to 2006. Data were collected from questionnaires that were sent to all 750 secondary or tertiary perinatal care centers in Japan.
Results: Eighty-two cases (14 with fetal hydrops) were analyzed (supraventricular tachycardia [SVT], n = 52; atrial flutter [AFL], n = 23; and ventricular tachycardia, n = 7). The overall mortality was 3.7%. Intrauterine treatment was performed for 41 fetuses (50.0%). Digoxin, flecainide and sotalol were mainly used for SVT and AFL. Fetal tachycardia resolved in 90.0% (27/30) of the cases without fetal hydrops and 90.9% (10/11) of the cases with fetal hydrops. Intrauterine treatment significantly reduced the incidence of cesarean delivery (29.3 vs. 70.7%, p < .01), preterm birth (12.2 vs. 41.5%, p = .02) and neonatal arrhythmias (48.8 vs. 78.0%, p = .01) in comparison to untreated fetuses.
Conclusions: This nationwide survey revealed that intrauterine treatment was performed for approximately half of the cases of fetal tachycardia and was associated with lower rates of cesarean delivery, premature birth and neonatal arrhythmias in comparison to untreated fetuses.
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http://dx.doi.org/10.1080/14767058.2017.1350159 | DOI Listing |
Mol Med Rep
March 2025
Department of Pathology, Aretaieion University Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Intrauterine growth restriction (IUGR) is the second most common obstetric complication after preterm labor. Appropriate trophoblast differentiation and placental structure, growth and function are key for the maintenance of pregnancy and normal fetal growth, development and survival. Extravillous trophoblast cell proliferation, migration and invasion are regulated by molecules produced by the fetomaternal interface, including autocrine factors produced by the trophoblast, such as insulin‑like growth factor (IGF)‑1.
View Article and Find Full Text PDFDiscov Oncol
January 2025
Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, No 218 Jixi Road, Hefei, 230022, China.
Background: Whether localized surgical treatment has advantages over traditional hormone therapy for young women who desire to preserve their fertility and have Stage 1a and Grade 1 endometrial cancer.
Case Presentation: We present a case study of a patient who was diagnosed with endometrial cancer (Grade 1a, Stage 1) and was experiencing infertility. The patient underwent conservative surgical treatment and was able to successfully conceive through in vitro fertilization (IVF).
F S Rep
December 2024
Ferring Pharmaceuticals Inc., Parsippany, New Jersey.
Objective: To evaluate the current utilization of advanced practice providers (APPs) within the field of reproductive endocrinology and infertility.
Design: Cross-sectional.
Setting: Web-based.
Curr Pharm Des
January 2025
Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Intrauterine adhesion (IUA) is a condition caused by damage to the basal uterine layer which can lead to partial or full occlusion of the uterine cavity. Although traditional treatment options have been useful in mild and moderate cases, they have been unsatisfactory in severe IUA cases. Therefore, it is essential to improve the treatment strategies of IUA.
View Article and Find Full Text PDFInt J Surg Case Rep
January 2025
Third Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Greece; Assisting Nature, Centre of Reproduction and Genetics, Thessaloniki, Greece. Electronic address:
Introduction: Cervical pregnancy is a rare kind of ectopic pregnancy. Heterotopic pregnancy is a condition, where we have one sac in the uterus and one in another location, usually because of IVF treatment. This scenario can become a life-threatening condition, if remain untreated.
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