Acetylated Furostene Glycosides from Solanum gilo Fruits.

In continuation of our work on a traditional mixture of spices called "Nkui", used in Cameroon for its influence on women's reproductive health, we investigated the chemical composition of , one component of "Nkui". A methanolic extract was studied in detail. After dereplication of several known compounds, two furo-5-stene-derived saponin glycosides with acetylated sugar moieties were isolated. By extensive 1- and 2D NMR experiments and HR-MS and GC-MS methods, the structures were elucidated as 26-[(3‴,4‴,6‴-tri-O-acetyl)--D-glucopyranosyloxy]-22-hydroxyfurost-5-en-3-yl-O--L-rhamnopyranosyl-(1″→2')--D-glucopyranoside () and 26-[(3‴,4‴,6‴-tri-O-acetyl)--D-glucopyranosyloxy]-22-hydroxyfurost-5-en-3-yl-[O--L-rhamnopyranosyl-(1''''→4')-O--L-rhamnopyranosyl-(1″→2')]--D-glucopyranoside (), both new natural compounds.