Arteriosclerotic heart disease is now the most important cause of morbidity and mortality in the elderly. Clinical presentation may be less typical than in younger patients, and therefore, a high index of suspicion is necessary. Although selectivity is required in regard to investigations, age should not deter the physician from establishing a diagnosis and quantifying the extent of the coronary artery disease. In this way, management will prove rewarding in terms of both symptomatic relief and prolonged survival with improved quality of life.
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Heliyon
January 2025
Department of Cardiovascular Medicine, The Second Affiliated Hospital of University of South China, Key Laboratory of Heart Failure Prevention & Treatment of Hengyang, Clinical Medicine Research Center of Arteriosclerotic Disease of Hunan Province, Hengyang, Hunan, China.
Background: Pulmonary fibrosis (PF) is an irreversible and usually fatal lung disease. In recent years, the therapeutic role of exosomes derived from mesenchymal stem cells (MSC-exos) in anti-fibrotic treatment has received much attention. In this study, we aimed to determine the anti-fibrotic properties and related molecular mechanisms of MSC-exos in Bleomycin(BLM)-induced PF.
View Article and Find Full Text PDFClin Cardiol
January 2025
Department of Cardiology, Affiliated Hospital of Jiaxing University, Jiaxing, China.
Background: Heart failure is extremely harmful to human health and social economics. The purpose of standardized heart failure management center (SHFMC) is to correct the non-standardization of heart failure treatment.
Hypothesis: SHFMC has a positive impact on the management and prognosis of patients with chronic heart failure (CHF).
J Tehran Heart Cent
January 2024
Department of Anatomy, Physiology and Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
Background: Cardiovascular disease (CVD) is one of the principal causes of mortality in the world. Various factors have been identified in the pathogenesis of CVD. Leukemia inhibitory factor (LIF) as a secretory cytokine is one of these factors.
View Article and Find Full Text PDFAdv Sci (Weinh)
December 2024
Clinical Research Institute, The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, P. R. China.
J Endovasc Ther
October 2024
Department of Vascular and Endovascular Surgery, Univ Brest, CHU Brest, UMR 1101 LaTIM, Brest, France.
Purpose: Limited data are available regarding endovascular therapy of arteriosclerotic lesions of the deep femoral artery (DFA). In this study, we compare the outcomes of atherectomy combined with drug-coated balloon (DCB) angioplasty and open repair of DFA lesions.
Methods: This is a multicenter retrospective registry of patients with peripheral artery occlusive disease Rutherford categories 2 to 5 treated by surgical profundaplasty (SP) or atherectomy followed by DCB for DFA lesions (symptomatic DFA).
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