Medical Physics is the scientific healthcare profession concerned with the application of the concepts and methods of physics in medicine. The European Federation of Organisations for Medical Physics (EFOMP) acts as the umbrella organization for European Medical Physics societies. Due to the rapid advancements in related scientific fields, medical physicists must have continuous education through workshops, training courses, conferences, and congresses during their professional life. The latest developments related to this increasingly significant medical speciality were presented during the 1st European Congress of Medical Physics 2016, held in Athens, September 1-4, 2016, organized by EFOMP, hosted by the Hellenic Association of Medical Physicists (HAMP), and summarized in the current volume.
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http://dx.doi.org/10.1016/j.ejmp.2017.07.001 | DOI Listing |
Eur J Nucl Med Mol Imaging
January 2025
Departments of Radiology and Medical Physics, University of Wisconsin - Madison, Madison, WI, 53705, USA.
Purpose: Trophoblast cell-surface antigen 2 (Trop2) is overexpressed in various solid tumors and contributes to tumor progression, while its expression remains low in normal tissues. Trop2-targeting antibody-drug conjugate (ADC), sacituzumab govitecan-hziy (Trodelvy), has shown efficacy in targeting this antigen. Leveraging the enhanced specificity of ADCs, we conducted the first immunoPET imaging study of Trop2 expression in gastric cancer (GC) and triple-negative breast cancer (TNBC) models using Zr-labeled Trodelvy ([Zr]Zr-DFO-Trodelvy).
View Article and Find Full Text PDFOrthopadie (Heidelb)
January 2025
Klinik für Handchirurgie und Orthopädie, Spital Langenthal, Spital Region Oberaargau SRO AG, Langenthal, Schweiz.
Pain around the first ray of the hand, particularly in the thumb area, is a frequent clinical problem that can have various causes. This article explores the most important differential diagnoses, including thumb carpometacarpal (CMC-I) osteoarthritis (rhizarthrosis), de Quervain's stenosing tenosynovitis, carpal tunnel syndrome and Wartenberg's syndrome. A detailed medical history, targeted clinical examination and if necessary the use of modern imaging techniques are crucial for making the diagnosis.
View Article and Find Full Text PDFMed Phys
January 2025
School of Computer Science and Engineering, Beihang University, Beijing, China.
Background: Computed tomography angiography (CTA) is used to screen for coronary artery calcification. As the coronary artery has complicated structure and tiny lumen, manual screening is a time-consuming task. Recently, many deep learning methods have been proposed for the segmentation (SEG) of coronary artery and calcification, however, they often neglect leveraging related anatomical prior knowledge, resulting in low accuracy and instability.
View Article and Find Full Text PDFMed Phys
January 2025
Deparment of Radiation Oncology, Duke University, Durham, North Carolina, USA.
Background: Stereotactic radiosurgery (SRS) is widely used for managing brain metastases (BMs), but an adverse effect, radionecrosis, complicates post-SRS management. Differentiating radionecrosis from tumor recurrence non-invasively remains a major clinical challenge, as conventional imaging techniques often necessitate surgical biopsy for accurate diagnosis. Machine learning and deep learning models have shown potential in distinguishing radionecrosis from tumor recurrence.
View Article and Find Full Text PDFJ Acoust Soc Am
January 2025
Key Laboratory of Modern Acoustics (MOE), School of Physics, Collaborative Innovation Centre of Advanced Microstructures, Nanjing University, Nanjing 210093, China.
In thermal therapies, accurate estimation of in-tissue power deposition density (PDD) is essential for predicting temperature distributions over time or regularizing temperature imaging. Based on our previous work on ultrasound thermometry, namely, multi-thread thermal strain imaging (MT-TSI), this work develops an in vivo PDD estimation method. Specifically, by combining the TSI model infinitesimal echo strain filter with the bio-heat transfer theory (the Pennes equation), a finite-difference time-domain model is established to allow online extraction of the PDD.
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