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Effect of a Ketogenic Diet on Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Progression: A Randomized Controlled Trial.
JGH Open
January 2025
Division of Gastroenterology, Department of Medicine Chulalongkorn University Bangkok Thailand.
Background: Despite the popularity of a ketogenic diet, no randomized, controlled trials have evaluated its efficacy on metabolic dysfunction-associated steatotic liver disease (MASLD) progression.
Methods: We conducted an 8-week, open-label, randomized controlled trial involving 24 patients with MASLD who were randomly assigned to either the home delivery ketogenic diet or a nutrition education program on adherence to the DASH diet. The primary outcome was a reduction in hepatic steatosis as measured by transient elastography.
The Emerging Role of Sonoelastography in Pregnancy: Applications in Assessing Maternal and Fetal Health.
Diagnostics (Basel)
December 2024
Radiology and Medical Imaging Department, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj 16278, Saudi Arabia.
Sonoelastography, a novel ultrasound-based technique, is emerging as a valuable tool in prenatal diagnostics by quantifying tissue elasticity and stiffness in vivo. This narrative review explores the application of sonoelastography in assessing maternal and fetal health, with a focus on cervical, placental, pelvic floor, and fetal tissue evaluations. In the cervix, sonoelastography aids in predicting preterm birth and assessing labor induction success.
View Article and Find Full Text PDFAcoustic Radiation Force Optical Coherence Elastography of the Crystalline Lens: Safety.
Transl Vis Sci Technol
December 2024
Department of Biomedical Engineering, University of Houston, Houston, TX, USA.
Purpose: To assess the safety of acoustic radiation force optical coherence elastography in the crystalline lens in situ.
Methods: Acoustic radiation force (ARF) produced by an immersion single-element ultrasound transducer (nominal frequency = 3.5 MHz) was characterized using a needle hydrophone and used for optical coherence elastography (OCE) of the crystalline lens.
Lubiprostone Reduces Fat Content on MRI-PDFF in Patients With MASLD: A 48-Week Randomised Controlled Trial.
Aliment Pharmacol Ther
February 2025
Liver Unit, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada.
Article Synopsis
- A 48-week study was conducted to evaluate the safety and effectiveness of the laxative lubiprostone in patients with metabolic dysfunction-associated steatotic liver disease (MASLD), showing promising results.
- Lubiprostone significantly reduced liver fat content compared to placebo, although it did not significantly impact fibrosis scores or serum ALT levels.
- While the treatment was generally tolerated, with only one case of severe diarrhea in the lubiprostone group, further research is needed to confirm its efficacy for MASLD.
[Comparison of the nutritional structure of patients with non-alcoholic fatty liver disease with the most significant nutrition patterns for health].
Vopr Pitan
November 2024
Federal Research Centre of Nutrition, Biotechnology and Food Safety, 109240, Moscow, Russian Federation.
Article Synopsis
- - Patients with non-alcoholic fatty liver disease (NAFLD) show impaired nutritional habits, and certain dietary patterns like the Mediterranean, vegetarian, and DASH diets can help prevent the disease.
- - The study involved analyzing the diets of 613 Russian patients with NAFLD and a control group, using data collected from 2021 to 2023, including assessment of liver conditions through advanced imaging techniques.
- - Findings revealed significant differences in food intake between NAFLD patients and healthy individuals, with NAFLD patients consuming less dairy, legumes, healthy fats, fish, vegetables, and nuts, while consuming more meat, compared to recommended dietary patterns.
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