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http://dx.doi.org/10.1002/acm2.12133 | DOI Listing |
Med Phys
January 2025
Department of Radiation Oncology, Stanford University, Palo Alto, California, USA.
Background: Dosimetric commissioning and quality assurance (QA) for linear accelerators (LINACs) present a significant challenge for clinical physicists due to the high measurement workload and stringent precision standards. This challenge is exacerbated for radiosurgery LINACs because of increased measurement uncertainty and more demanding setup accuracy for small-field beams. Optimizing physicists' effort during beam measurements while ensuring the quality of the measured data is crucial for clinical efficiency and patient safety.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Institute of High Pressure Physics, Polish Academy of Sciences, Warsaw 01-142, Poland.
Ultrasmall micro-light-emitting diodes (μLEDs), sized below 10 μm, are indispensable to create the next-generation augmented and virtual reality (AR/VR) devices. Their high brightness and low power consumption could not only enhance the user experience by providing vivid and lifelike visuals but also extend device longevity. However, a notable challenge emerges: a decrease in efficiency with a reduced size.
View Article and Find Full Text PDFJCI Insight
January 2025
Department of Biomedical Engineering, Oregon Health and Science University, Portland, United States of America.
Spatial profiling of tissues promises to elucidate tumor-microenvironment interactions and generate prognostic and predictive biomarkers. We analyzed single-cell, spatial data from three multiplex imaging technologies: cyclic immunofluorescence (CycIF) data we generated from 102 breast cancer patients with clinical follow-up, and publicly available imaging mass cytometry and multiplex ion-beam imaging datasets. Similar single-cell phenotyping results across imaging platforms enabled combined analysis of epithelial phenotypes to delineate prognostic subtypes among estrogen-receptor positive (ER+) patients.
View Article and Find Full Text PDFRSC Adv
January 2025
Institute of Atomic and Molecular Sciences, Academia Sinica Taipei 106 Taiwan
Extreme ultraviolet (EUV) lithography is a cutting-edge technology in contemporary semiconductor chip manufacturing. Monitoring the EUV beam profiles is critical to ensuring consistent quality and precision in the manufacturing process. This study uncovers the practical use of fluorescent nanodiamonds (FNDs) coated on optical image sensors for profiling EUV and soft X-ray (SXR) radiation beams.
View Article and Find Full Text PDFPhys Med
January 2025
IRCCS San Raffaele Scientific Institute, Experimental Imaging Center, Milan, Italy. Electronic address:
Purpose: Minibeam radiotherapy (MBRT) uses small parallel beams of radiation to create a highly modulated dose pattern. The aim of this study is to develop an optical radioluminescence imaging (RLI) approach to perform real-time dose measurement for MBRT.
Methods: MBRT was delivered using an image-guided small animal irradiator equipped with a custom collimator.
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