Purpose: To investigate beam quality correction, () and phantom scatter correction, () for lithium formate dosimeter as a function of distance r along the transverse axis of the high-energy brachytherapy sources Co, Cs, Ir and Yb using the Monte Carlo-based EGSnrc code system.
Materials And Methods: The brachytherapy sources investigated in this study are BEBIG High Dose Rate (HDR) Co (model Co0.A86), Cs (model RTR), HDR Ir (model Microselectron) and HDR Yb (model 4140). The solid phantom materials investigated are PMMA, polystyrene, solid water, virtual water, plastic water, RW1, RW3, A150 and WE210.
Result: () is about unity and distance independent fo Co, Cs and Ir brachytherapy sources, whereas for the Yb source, () increases gradually to about 4 % larger than unity at a distance of 15 cm along the transverse axis of the source. For Co source, phantoms such as polystyrene, plastic water, solid water, virtual water, RW1, RW3 and WE210 are water-equivalent but PMMA and A150 phantoms show distance-dependent () values. For Cs and Ir sources, phantoms such as solid water, virtual water, RW1, RW3 and WE210 are water-equivalent. However, phantoms such as PMMA, plastic water, polystyrene and A150 showed distance-dependent () values, for these sources. For Yb source, all the investigated phantoms show distance-dependent () values.
Conclusion: () is about unity and distance independent for Co, Cs and Ir brachytherapy sources. Phantoms such as solid water, virtual water, RW1, RW3 and WE210 are water-equivalent for Co, Cs and Ir brachytherapy sources. For Yb source, all the investigated phantoms show distance-dependent () values.
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http://dx.doi.org/10.4103/jmp.JMP_95_16 | DOI Listing |
Med Phys
January 2025
Department of Radiation Oncology, Inha University Hospital, Incheon, Republic of Korea.
Background: High-dose-rate (HDR) brachytherapy using Iridium-192 as a radiation source is widely employed in cancer treatment to deliver concentrated radiation doses while minimizing normal tissue exposure. In this treatment, the precision with which the sealed radioisotope source is delivered significantly impacts clinical outcomes.
Purpose: This study aims to evaluate the feasibility of a new four-dimensional (4D) in vivo source tracking and treatment verification system for HDR brachytherapy using a patient-specific approach.
Rep Pract Oncol Radiother
December 2024
Department of Biomedical Physics, Faculty of Physics, Adam Mickiewicz University, Poznań, Poland.
Background: The purpose of this study is to determine the effect of the type of I-125 radioactive source on dose distribution in the planning process of ultra-low dose rate (uLDR) prostate brachytherapy.
Material And Methods: 7 patients who had undergone brachytherapy in our center were included in the study. Dose in five geometrical points were analyzed for 12 types of implants that are available on the market.
EJNMMI Radiopharm Chem
December 2024
The Hevesy Laboratory, DTU Health Technology, Frederiksborgvej 399, 4000, Roskilde, Denmark.
Background: Brachytherapy (BT) is routinely used in the treatment of various cancers. Current BT relies on the placement of large sources of radioactivity at the tumor site, requiring applicators that may cause local traumas and lesions. Further, they suffer from inflexibility in where they can be placed and some sources reside permanently in the body, causing potential long-term discomfort.
View Article and Find Full Text PDFBrachytherapy
December 2024
Department of Radiation Oncology, University of Taxes, Southwestern Medical Center, Dallas, Texas.
Background: Cervical cancer is the second most common cancer among women in Nigeria where, the gap between need for, and access to, radiation therapy including brachytherapy is significant. This report documents the implementation of the first three-dimensional high-dose-rate (3D-HDR) brachytherapy service for cervical cancer in Nigeria.
Purpose: This report details the steps taken to implement the 3D-HDR brachytherapy program, the challenges faced, and the adaptive strategies employed to overcome them.
J Contemp Brachytherapy
October 2024
Department of Radiation Oncology, Cancer Institute, Imam Khomeini Hospital Complex, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Purpose: Non-melanoma skin cancer (NMSC) is the most prevalent cancer worldwide, particularly affecting head and neck region. Surgical excision, especially Moh's microsurgery, is the gold standard for treatment. However, certain patients' factors, such as age, comorbidities, and tumor location, require alternative therapies.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!