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Sub-therapeutic darunavir concentration and garlic consumption; a «Mediterranean» drug-food interaction, about 2 cases.
Eur J Clin Pharmacol
October 2017
Aix-Marseille University, Marseille, France.
Darunavir pharmacokinetics throughout pregnancy and postpartum.
J Int AIDS Soc
January 2016
Molecular and Clinical Pharmacology, Royal Liverpool University Hospital, Liverpool, UK.
Introduction: Antiretroviral therapy is recommended during pregnancy for prevention of mother-to-child transmission (MTCT) of HIV. Physiological changes during pregnancy are known to affect the pharmacokinetics (PK) of protease inhibitors (PIs), leading to lower exposures in pregnant women. Here we examine the PK of DRV/r 800/100 mg once daily (OD) over the course of pregnancy and postpartum (PP).
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