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Streptococci Biotypes in Primary and Permanent Caries: A Case-Control Study.
Int J Clin Pediatr Dent
September 2024
Department of Microbiology, Dr Harvansh Singh Judge Institute of Dental Sciences and Hospital, Panjab University, Chandigarh, India.
Background And Aim: Streptococci, mainly mutans streptococci, are known as the causative microbes of dental caries, but there is limited clarity about their impact on the tooth level and the distribution of streptococci species in different dentition stages. This study evaluates the distribution of streptococci species in primary and permanent teeth in children and adolescents with caries.
Materials And Methods: The study population consisted of two groups: subjects with caries in primary teeth aged 2-5 years and adolescents with caries in permanent teeth aged 12-15 years.
Selective Biofilm Inhibition through Mucin-Inspired Engineering of Silk Glycopolymers.
J Am Chem Soc
December 2024
Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.
Mucins are key components of innate immune defense and possess remarkable abilities to manage pathogenic microbes while supporting beneficial ones and maintaining microbial homeostasis at mucosal surfaces. Their unique properties have garnered significant interest in developing mucin-inspired materials as novel therapeutic strategies for selectively controlling pathogens without disrupting the overall microbial ecology. However, natural mucin production is challenging to scale, driving the need for simpler materials that reproduce mucin's bioactivity.
View Article and Find Full Text PDFTailoring magnesium-doped coatings for improving surface and biological properties of titanium-based dental implants.
Colloids Surf B Biointerfaces
February 2025
Department of Prosthodontics and Periodontology, Piracicaba Dental School, Universidade Estadual de Campinas (UNICAMP), Piracicaba, São Paulo 13414-903, Brazil. Electronic address:
Physicochemical modifications of biomaterials have been proposed to overcome bone integration impairment and microbial infections. The magnesium (Mg) incorporation on dental implant surfaces has shown positive results in bone-to-implant contact and in the reduction of microbial colonization. Here, we explored the potential of using different Mg precursors to synthesize coatings via plasma electrolytic oxidation (PEO) on commercially pure titanium (cpTi), aiming to optimize the surface and biological properties.
View Article and Find Full Text PDFNicotine promotes pathogenic bacterial growth and biofilm formation in peri-implant.
J Med Microbiol
October 2024
Department of Stomatology, Affiliated Hospital of Yunnan University, Kunming, Yunnan 650000, PR China.
Article Synopsis
- Peri-implantitis is a disease linked to plaque that can cause the loss of dental implants, with smoking worsening the condition and treatment outcomes.
- The study focused on how nicotine affects inflammation and the growth of bacteria that contribute to peri-implantitis by examining specific markers (AHR, IL-6, IL-22) and through experiments with bacterial suspensions treated with varying nicotine concentrations.
- Results showed that nicotine not only increases the levels of inflammatory markers but also enhances bacterial growth and biofilm formation, indicating that smoking may worsen peri-implantitis progression.
Biofilm formation of Streptococcus mutans, Streptococcus sanguinis, Staphylococcus epidermidis, Staphylococcus aureus, Lactobacillus casei, and Candida Albicans on 5 thermoform and 3D printed orthodontic clear aligner and retainer materials at 3 time points: an in vitro study.
BMC Oral Health
September 2024
Department of Dental Anatomy, Azad University of Medical Sciences, Tehran, Iran.
Introduction: Orthodontic clear aligners and retainers have numerous advantages that is making them ever increasingly popular. However, they might, similar to any other oral appliance, contribute to biofilm formation and finally dental caries or white spot lesions or gingival inflammations. The literature on biofilm formation on orthodontic clear appliances is very scarce and limited to a few microorganisms and materials.
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