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Background: Millions of people suffer from traumatic brain injury (TBI) annually and many subsequently develop AD-like characteristics, but the processes occurring in the brain and the reasons for the acquisition of AD-like dementia are unknown. TBI is the leading cause of mortality in young adults and causes a huge socioeconomic burden. Improving outcomes in these patients would be a significant public health benefit.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
Harvard University School of Medicine, Cambridge, MA, USA.
Background: Exposure to repetitive head impacts (RHI) is associated with the neurodegenerative tauopathy chronic traumatic encephalopathy (CTE). There is substantial heterogeneity in the clinical presentation of CTE. Younger age of first exposure (AFE) to American football has not been associated with odds or severity of CTE.
View Article and Find Full Text PDFIdentifying mild traumatic brain injury in the post-acute polytrauma setting: a scoping review of diagnostic approaches and screening tools.
Brain Inj
January 2025
St. John's Rehab Research Program, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Objective: Mild traumatic brain injury (mTBI) is frequently overlooked in polytrauma patients due to the overshadowing of more severe injuries, a fact that makes its identification in post-acute settings challenging since symptoms overlap with other conditions and no validated diagnostic tools exist. To address this gap, this scoping review explored the literature on mTBI diagnosis in post-acute civilian polytrauma settings.
Methods: By utilizing the Arksey and O'Malley framework and PRISMA-ScR guidelines, the review focused on studies from 2010 to 2024 related to delayed mTBI diagnosis in adults.
A Narrative Review of Combat Sports Injuries With a Particular Focus on Cervical Spine Injuries.
Cureus
December 2024
Orthopedic Surgery, National and Kapodistrian University of Athens, Attikon Hospital, Athens, GRC.
Combat sports encompass a wide range of disciplines, each associated with distinct injury patterns and mechanisms. From karate to wrestling, athletes face varying degrees of injury risks, with common clinical presentations including head injuries, strains, sprains, fractures, and concussions. These injuries often result from dynamic movements, physical contact, and high-impact collisions inherent to combat sports.
View Article and Find Full Text PDFRelationship between language comprehension and chronic neurobehavioral symptoms in adults with mild traumatic brain injury.
Brain Inj
December 2024
Department of Communication Sciences and Disorders, University of Texas Health San Antonio, San Antonio, Texas, USA.
Primary Objectives: Annually, millions of Americans sustain mild traumatic brain injuries (mTBI), and some may experience neurobehavioral symptoms (NBS), like slow processing speed that persist chronically or longer than 6 months post injury. In turn, cognitive processes like language comprehension may be compromised. This study investigates the relationship between NBS and language comprehension in individuals with mTBI history and low or high NBS.
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