A series of 30 sclerotioramine derivatives (2-31) of the natural compound, (+)-sclerotiorin (1), has been successfully semi-synthesized by a one-step reaction with high yields (up to 80%). The structures of these new derivatives were established by extensive spectroscopic methods and single-crystal X-ray diffraction analysis for 3, 6, and 10. (+)-Sclerotiorin (1) and its semisynthetic derivatives (2-31) were evaluated for their antifouling activity. Most of them except 6, 7, 8, 12, and 28 showed potent antifouling activity against the larval settlement of the barnacle Balanus amphitrite. More interestingly, most of the aromatic amino-derivatives (13-17, 19-21, 23, 25-27, and 29-31) showed strong antifouling activity; however, only two aliphatic amino-derivatives (5 and 10) had the activity.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10126-017-9760-x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Stable Antifouling and Antibacterial Coating Based on Assembly of Copper-Phenolic Networks.
ACS Appl Bio Mater
January 2025
Department of Chemical and Materials Engineering, University of Alberta, Edmonton, Alberta T6G 1H9, Canada.
Biofilm formation on medical devices has become a worldwide issue arising from its resistance to bactericidal agents and presenting challenges to eradicating biofouling adhesion, especially in biological fluids. Metal-phenolic networks have been demonstrated as a versatile and efficient strategy to prevent biofilm formation by endowing medical devices with prolonged antifouling and antibacterial activities in a one-step surface modification. In this study, we report a simple and environmentally friendly method using coordination chemistry between copper ions (Cu) and dopamine-containing copolymer to fabricate metal-phenolic network-based coatings.
View Article and Find Full Text PDFDevelopment of a Highly Hydrophobic Micro/Nanostructured Nanocomposite Coating of PLA-PEG-Cloisite 20A Nanoclay with Excellent Hemocompatibility and Rapid Endothelialization Properties for Cardiovascular Applications.
ACS Appl Mater Interfaces
January 2025
Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran 1416753955, Iran.
Despite the unique properties of clay nanocomposites for cardiovascular applications, there are few data on the hemocompatibility of these nanomaterials. This study represents the first comprehensive investigation of the hemo/biocompatibility of clay nanocomposites . Nanocomposite coatings of polylactic acid (PLA)-polyethylene glycol (3 wt %)-Cloisite20A nanoclay (3 wt %) were produced using electrospraying technique as potential drug-eluting stent (DES) coatings.
View Article and Find Full Text PDFBioinspired Liquid Pockets with Externally Induced Internal Microscale Flow.
Adv Mater
January 2025
School of Life Sciences, Xiamen University, Xiamen, 361102, China.
The gastric mucosal barrier, through its gastric pits, serves as a pathway for secretions, ensuring that mucus produced by the gastric glands is transferred to the gastric lumen, providing stable protection. Here a bioinspired liquid pockets material is shown, composed of a thermo-driven hydrogel that acts as an external activation unit to release interflowing liquid responsively, and porous matrices that serve as interconnected pockets to transfer it, enabling controlled internal flow and adaptive barrier functionality. Experiments and theoretical analysis demonstrate the stability and regulatory mechanisms of these liquid pockets, based on the interconnected pockets between the external activation unit and internal fluid flow.
View Article and Find Full Text PDFMitigating oxidative stress in oyster larvae: Curcumin promotes enhanced redox balance, antioxidant capacity, development, and resistance to antifouling compounds.
Aquat Toxicol
December 2024
Univ Brest, Ifremer, CNRS, IRD, LEMAR, IUEM, F-29280 Plouzané, France. Electronic address:
Curcumin (CUR) is a natural compound recognized for stimulating the expression of antioxidant genes. This characteristic has been used to promote animal health and production in aquaculture settings. We hypothesized that supplementing embryos of Crassostrea gigas oysters with CUR would improve their antioxidant capacity, development, and resilience to stress.
View Article and Find Full Text PDFAn Array of Glucose Nanozymes That Can Selectively Detect Glucose in Whole Blood.
ACS Sens
January 2025
School of Chemistry, Australian Centre for Nanomedicine, The University of New South Wales, Sydney, NSW 2052, Australia.
Achieving sensors that can sensitively and selectively quantify levels of analytes in complex biofluids such as blood remains a significant challenge. To address this, we synthesized an array of isolated carbon nanochannels on a flat gold electrode that function as molecular sieves to prevent protein fouling and eliminate the need for antifouling layers. Utilizing a two-step pulsed technique, a reductive pulse expels negative interferences and fouling molecules followed by an oxidative pulse that oxidizes glucose at the bottom of the channel and on the gold surface.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!