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| http://dx.doi.org/10.1007/s11999-017-5431-5 | DOI Listing |
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PATCH (Preferred Attachment Strategy for Optimal Electrocardiograms)-1 Study.
Clin Res Cardiol
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Division of Cardiovascular Health and Disease, Department of Biomedical Informatics, Department of Environmental Health, University of Cincinnati College of Medicine, University of Cincinnati, Cincinnati, USA.
Article Synopsis
- The PATCH-1 study compared two types of 12-lead electrocardiograms (ECGs) – the standard S-ECG and a new patch ECG (P-ECG), to see which one performed better in patients with stable cardiovascular conditions.
- 200 participants were involved, and results showed that the P-ECG was faster to administer (about 1.4 minutes) and had fewer issues with artifacts affecting readings compared to the S-ECG (6.5% vs. 15%).
- Most participants either preferred the P-ECG (47%) or were indifferent (52%), and both types of ECGs provided similar findings regarding heart health metrics.
Dynamic synthetic-scanning photoacoustic tracking monitors hepatic and renal clearance pathway of exogeneous probes in vivo.
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Medical Research Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510080, China.
Advancements in precision medicine necessitate understanding drug clearance pathways, especially in organs like the liver and kidneys. Traditional techniques such as PET/CT pose radiation hazards, whereas optical imaging poses challenges in maintaining both depth penetration and high resolution. Moreover, very few longitudinal studies have been performed for drug candidates for different symptoms.
View Article and Find Full Text PDFTransmission Electron Microscopy of Coral Tissue.
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November 2024
Department of Biology and Marine Biology, University of North Carolina Wilmington, Wilmington, North Carolina.
Coral reefs are invaluable ecosystems that are under threat from various anthropogenic stressors. There has been a recent increase in the diagnostic tools utilized to understand how these threats impact coral reef health. Unfortunately, the application of diagnostic tools like transmission electron microscopy (TEM) is not as standardized or developed in coral research as in other research fields.
View Article and Find Full Text PDFRevisiting the Pattern of Loss of β-Cell Function in Preclinical Type 1 Diabetes.
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Type 1 diabetes (T1D) results from β-cell destruction due to autoimmunity. It has been proposed that β-cell loss is relatively quiescent in the early years after seroconversion to islet antibody positivity (stage 1), with accelerated β-cell loss only developing around 6-18 months prior to clinical diagnosis. This construct implies that immunointervention in this early stage will be of little benefit, since there is little disease activity to modulate.
View Article and Find Full Text PDFOnset and progression of postmortem histological changes in the central nervous system of RccHan: WIST rats.
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Death initiates a cascade of physiological and biochemical alterations in organs and tissues, resulting in microscopic changes that challenge the histopathological evaluation. Moreover, the brain is particularly susceptible to artifacts owing to its unique composition and its location within the cranial vault. The aim of this study was to compile and illustrate the microscopic changes in the central nervous system (CNS) of rats subjected to delayed postmortem fixation.
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