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Retinoic Acid Puts Hematopoietic Stem Cells Back To Sleep. | LitMetric
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Retinoic Acid Puts Hematopoietic Stem Cells Back To Sleep.

Alexandra Rundberg Nilsson Cornelis Jan Pronk

Cell Stem Cell

Medical Faculty, Division of Molecular Hematology, Institution for Laboratory Medicine, Lund University, 221 84 Lund, Sweden; Medical Faculty, Lund Stem Cell Center, Lund University, 221 84 Lund, Sweden; Department of Pediatric Oncology/Hematology, Skåne University Hospital, 221 85 Lund, Sweden. Electronic address:

Published: July 2017

Dormant hematopoietic stem cells (dHSCs) display superior serial reconstitution capacity compared to active HSCs, although their role in normal hematopoiesis has not been thoroughly investigated. Recently in Cell, Cabezas-Wallscheid et al. (2017) demonstrate involvement of retinoic acid signaling in murine dHSCs for preservation of the HSC pool.

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http://dx.doi.org/10.1016/j.stem.2017.06.002DOI Listing

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