A case of Clostridium septicum aortitis is reported. The patient did not present any colon tumor. She died in spite of surgery and i.v. antibiotics. To date C. septicum has been reported only in about 40 cases of infectious aortitis, a disease with unspecific clinical presentation and a high mortality rate. A high index of suspicion is warranted for an early diagnosis which can be made mainly by blood cultures and contrast-enhanced CT-scan. Only starting without delay a treatment that combines antibiotics with surgery can improve a prognosis that remains nevertheless globally bad.
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