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Clinical Outcomes of Liver Abscesses in Adults: A 10-Year Experience at a Tertiary Care Center in Northern India.
Cureus
December 2024
Department of Anatomy, Ganesh Shankar Vidyarthi Memorial Medical College, Kanpur, IND.
Purpose Hepatic abscesses remain a significant clinical challenge due to high morbidity and mortality. This research aims to examine the etiological spectrum, management approaches, clinical features, and results in hepatic abscesses in a tertiary care facility in northern India, emphasizing the distinctions among pyogenic liver abscesses (PLAs) and amoebic liver abscesses (ALAs). Methods This retrospective study was done at GSVM Medical College, Kanpur, analyzing 725 patients with hepatic abscesses over a 10-year period.
View Article and Find Full Text PDFUnusual Findings of Human-Associated Four-Nucleated Species in Captive Wild Animals.
Animals (Basel)
January 2025
Department of Parasitology, Faculty of Pharmacy, Complutense University, Plaza Ramón y Cajal s/n, 28040 Madrid, Spain.
Several species of amoebae in the genus forming four-nucleated mature cysts are pathogenic, but their identification is challenging due to a lack of distinctive morphological traits. Furthermore, host species cannot reliably be used as a criterion for identification. In this study, several isolates of four-nucleated cyst-forming species from animals at the Zoo Aquarium of Madrid are genetically identified.
View Article and Find Full Text PDFAmoebae: beyond pathogens- exploring their benefits and future potential.
Front Cell Infect Microbiol
January 2025
Department of Biomedical Science and Technology, School of Biological Sciences, Ramakrishna Mission Vivekananda Educational and Research Institute (RKMVERI), Kolkata, India.
Amoebae, fascinatingly diverse protists, showcase a dual nature that positions them as both friends and foes in our world. These organisms, defined by their distinctive pseudopodia, span a spectrum from harmful to helpful. On the darker side, species like pose serious health risks, causing intestinal and liver diseases, while the infamous "brain-eating" leads to fatal primary amoebic meningoencephalitis (PAM), with a daunting 97% mortality rate.
View Article and Find Full Text PDFPrevalence and associated factors of intestinal parasitic infections in the Badi indigenous communities of Western Nepal.
J Health Popul Nutr
December 2024
Central Department of Zoology, Institute of Science and Technology, Tribhuvan University Central Campus, Kirtipur, Kathmandu, Nepal.
Despite years of a national deworming campaign, the incidence of intestinal parasitic infections (IPIs) remains relatively high among certain ethnic groups, with lifestyle factors distinct from those of the general population. Despite existing studies on the prevalence of IPIs, there is limited research exploring the contextual associated factors within the Badi Indigenous community. Our objective in this study was to assess the prevalence of IPIs in the indigenous Badi community of Gurbhakot Municipality, Surkhet, Nepal, considering socioeconomic, lifestyle, and behavioral factors.
View Article and Find Full Text PDFAGC family kinase of Entamoeba histolytica: Decoding the members biochemically.
PLoS Pathog
November 2024
Multidisciplinary Centre for Advanced Research and Studies, Jamia Millia Islamia, New Delhi, India.
Article Synopsis
- Entamoeba histolytica is a protozoan parasite that causes amoebiasis, a major global health issue, with complex mechanisms of virulence including endocytic processes and motility.
- Two kinases from the AGCK family, EhAGCK1 and EhAGCK2, have been studied, revealing that EhAGCK1 is specifically involved in trogocytosis while EhAGCK2 is engaged in all actin-dependent endocytic processes.
- The research highlights the distinct biochemical properties of these kinases, including their ion dependency and substrate specificity, and emphasizes their unique roles in related endocytic processes such as trogocytosis and phagocytosis.
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