Background And Purpose: In traditional medicine, herbal products still remain the principal source of pharmaceutical agents. The present study aimed to investigate the antifungal effects of and extracts on species.
Materials And Methods: The aqueous and ethanolic leaf extracts of and , collected from the mountainous regions of Iran, were screened in terms of antimicrobial activity against strains, using the agar well diffusion method. The minimum inhibitory concentration was determined by the microtitration technique.
Results: Overall, the results showed that the leaf extracts of and had strong antimicrobial activities. Also, based on the findings, leaf extracts exhibited higher antimicrobial activity. The ethanolic leaf extracts of and showed good antimicrobial activity against strains. However, the aqueous extracts did not show any major activities against the tested strains. On the other hand, the ethanolic extracts exhibited major antimicrobial properties against strains. The highest minimum inhibitory concentration was reported in leaf extracts.
Conclusion: The present results indicated some advantages of and leaf extracts, which could be applied for the treatment of microbial infections.
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http://dx.doi.org/10.18869/acadpub.cmm.2.1.30 | DOI Listing |
Braz J Microbiol
January 2025
Innovation and Drug Discovery, Sava Healthcare Limited, Research Center, MIDC, Block D1, Plot No. 17/6, Chinchwad, Pune, 411019, India.
Plant parts such as roots, bark, leaves, flowers, and fruits that hold ethnopharmacological significance are naturally prone to microbial contamination, influenced by environmental factors like moisture and humidity. This study focuses on assessing the microbial load in the raw material of Tribulus terrestris (TT). The primary bacterium isolated from the pulverized raw material was identified as Bacillus haynesii through 16S rRNA sequencing.
View Article and Find Full Text PDF<b>Background and Objective:</b> <i>Oroxylum indicum</i>, a plant commonly used in traditional medicine to address various human ailments, has recently gained attention as a promising candidate in this regard due to its rich phytochemical composition and potential antibacterial properties. This study was undertaken to evaluate the antibacterial efficacy of <i>O. indicum</i> extracts, specifically from its leaves and stems, against antibiotic-resistant bacteria.
View Article and Find Full Text PDFCurr Top Med Chem
January 2025
Medicinal Chemistry Department, Theodor Bilharz Research Institute Kornaish El Nile, Warrak El-Hadar, Imbaba (P.O. 30), Giza 12411, Egypt.
Background: Research into oxidative stress, cancer, and natural products revealed promising avenues for therapeutic intervention. Natural products are considered potent pharmaceuticals in combating oxidative stress and its relationship with cancer.
Methods: This study was carried out to evaluate the chemical profile and antioxidant activities using DPPH, ABTS, Phenanthroline, Cupric, Phosphomolybdenum, FRAP, Hydroxyl, Iron chelation in vitro assays, and anticancer properties by MTT method of Cistus creticus extracts.
Food Chem X
January 2025
Providence University, Department of Food and Nutrition, Taichung 43301, Taiwan.
Djulis ( Koidz.) is an endemic cereal plant to Taiwan that has been cultivated by Taiwanese aborigines for hundreds of years. Djulis Djulis is a well-known ruby cereal because it contains betanin and exhibits strong antioxidant activity.
View Article and Find Full Text PDFCerebral malaria (CM) is a severe complication of Plasmodium falciparum infection, with resistance to antimalarial drugs, including artemisinin-based combination therapies(ACTs), posing a significant threat. CD4+ naive cells expressing CCR7 are known to play a protective role, as they readily migrate to secondary lymphoid tissues activated by CCL19 chemokines. In an effort to address this challenge, we investigated the impact of Annona muricata, an herbaceous and immunomodulatory plant, on CCL19 concentration.
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