We should possibly revise our knowledge about risk assessment of splenectomized individuals with -thalassemia major. Besides their known risk of certain bacterial infection, they might be also in a risk of life-threatening primary cytomegalovirus (CMV) infection and end-, multi-organ disease, in the context of their immunosuppression status. Prompt and appropriate treatment initiation can be life saving.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494393PMC
http://dx.doi.org/10.1002/ccr3.1001DOI Listing

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