A synthetic strategy has been developed for the synthesis of 1-azaanthraquinones. This synthetic protocol consists of sequential Pd-catalyzed carbon-nitrogen bond formation followed by Lewis acid catalyzed intramolecular cyclization. The Pd-catalyzed aminated intermediate was isolated and characterized. This sequential reactions strategy provides a wide range of 1-azaanthraquinones with good yields.
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http://dx.doi.org/10.1021/acs.joc.7b01427 | DOI Listing |
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