Two new sterols, columnaristerols B () and C (), along with two known analogues, 5,6-epoxylitosterol () and litosterol (), were obtained from the octocoral . The structures of new sterols and were elucidated by using spectroscopic methods and comparing the spectroscopic data with those of known related metabolites. Sterol was found to suppress superoxide anion production and elastase secretion by human neutrophils.
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| http://dx.doi.org/10.3390/md15070212 | DOI Listing |
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Sterols from the Octocoral Nephthea columnaris.
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Graduate Institute of Marine Biology, National Dong Hwa University, Pingtung 944, Taiwan.
Two new sterols, columnaristerols B () and C (), along with two known analogues, 5,6-epoxylitosterol () and litosterol (), were obtained from the octocoral . The structures of new sterols and were elucidated by using spectroscopic methods and comparing the spectroscopic data with those of known related metabolites. Sterol was found to suppress superoxide anion production and elastase secretion by human neutrophils.
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Graduate Institute of Marine Biology, National Dong Hwa University, Pingtung 944, Taiwan; National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan; Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung 404, Taiwan; Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan. Electronic address:
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