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Rapid progression of a coronary artery aneurysm caused by IgG4-related disease.
Cardiovasc Pathol
May 2024
Department of Cardiology, Kindai University School of Medicine, Osaka Japan.
Article Synopsis
- IgG4-related disease (IgG4-RD) is a new fibro-inflammatory condition affecting various organs, and it can lead to serious heart issues like IgG4-related coronary artery aneurysms (IGCAs).
- A 60-year-old man with a known history of IgG4-RD experienced acute coronary syndrome due to rapid progression of an IGCA and related artery blockages, necessitating multiple surgical interventions.
- Close monitoring with imaging techniques like CT scans is crucial for detecting any enlargement of IGCAs early to prevent life-threatening complications.
Kyrieleis plaques: recognising a rare presentation of ocular inflammation.
Clin Exp Optom
November 2024
Ophthalmology Department, BronxCare Health System, Bronx, NY, USA.
Article Synopsis
- Kyrieleis plaques are segmented inflammatory deposits found along retinal arteries, mostly appearing unilateral and near areas of retinal infection or inflammation.
- These plaques are located within vessel walls, not in the lumen or surrounding tissues, and are often referred to as segmental retinal periarteritis.
- Diagnosis of Kyrieleis plaques is determined by exclusion, as they must be differentiated from other retinal vessel issues like emboli and artery sheathing, which may require prompt medical attention.
Retrospective assessment of porcine circovirus 3 (PCV-3) in formalin-fixed, paraffin-embedded tissues from pigs affected by different clinical-pathological conditions.
Porcine Health Manag
December 2022
Unitat Mixta d'Investigació IRTA-UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), 08193, Bellaterra, Barcelona, Catalonia, Spain.
Background: Porcine circovirus 3 (PCV-3) is a recently discovered pathogen of swine that has been associated with several conditions. However, many questions remain unanswered regarding its infection, especially in terms of pathogenesis and disease impact. The aim of the present study was to retrospectively investigate the presence of PCV-3 genome by real time quantitative PCR (qPCR) and in situ hybridization (ISH) on selected formalin-fixed paraffin-embedded tissues of pigs affected by different clinical conditions and histological lesions.
View Article and Find Full Text PDFFatal eosinophilic coronary periarteritis leads to dissection in a young patient: A case report.
J Cardiol Cases
February 2020
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Eosinophilic coronary periarteritis (ECPA) is a poorly studied type of coronary arteritis. It causes myocardial ischemia and most cases are diagnosed at autopsy. We report the case of a 35-year-old woman who presented with sudden unexpected cardiac arrest and was brought to the emergency ward.
View Article and Find Full Text PDFIgG4-related periaortitis/periarteritis: An under-recognized condition that is potentially life-threatening.
Mod Rheumatol
March 2019
e Department of Cardiology , Osaka Medical College, Osaka , Japan.
Periaortitis and periarteritis are one of the clinical features of IgG4-related disease. Such vascular manifestations are reported to be present in 10-30% of overall IgG4-related disease, and they may also appear as an isolated lesion of IgG4-related disease. As other types of large vessel vasculitis, IgG4-related vasculitis may cause significant clinical consequences.
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