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Treatment and Prevention of Adrenal Crisis and Family Education.
J Clin Res Pediatr Endocrinol
December 2024
Baskent University Faculty of Medicine, Department of Pediatric Endocrinology, Adana, Turkey.
Adrenal crisis is a life threatening complication of adrenal insufficiency (AI). Its treatment is urgent and parenteral hydrocortisone should be given at 10-15 times physiological doses in this situation. If hydrocortisone is not available, alternatively prednisolone or methyl prednisolone may be used.
View Article and Find Full Text PDFTrends in the market for drug delivery devices categorized as combination drugs and medical devices and regulatory challenges for autoinjectors in Japan.
Front Med Technol
August 2024
Department of Regulatory Science, Graduate School of Pharmaceutical Science, Meiji Pharmaceutical University, Tokyo, Japan.
Background: Although a variety of drug delivery devices have been launched in recent years, few studies have comprehensively investigated the market trends of combination drugs and medical devices approved or certified in Japan and the regulatory challenges related to their approval. Among the drug delivery devices, autoinjectors are more convenient than traditional prefilled syringes and are designed with safety features to prevent needlestick accidents, allowing self-injection by patients. Therefore, autoinjectors have been incorporated into the treatment of various diseases and have shown significant growth among drug delivery devices.
View Article and Find Full Text PDFEvaluation of the Functionality in an Emergency Department Setting of an Intravenous Protection Device to Prevent Self-Injection.
Med Devices (Auckl)
March 2024
Emergency Department, Mayo Clinic, Jacksonville, FL, USA.
Background: The United States has an opioid abuse crisis that has been increasing exponentially since 2013. In 2021, there were 220 deaths each day from opioid overdoses in the United States alone. Patients suffering from addiction often present to the emergency department (ED) anticipating that an intravenous (IV) catheter will be placed.
View Article and Find Full Text PDFHand function following accidental automatic animal syringe injector injuries.
Sci Rep
December 2022
Orthopedic Department, Emek Medical Center, Afula, Israel.
Accidental self-injection injury is a common occurrence among veterinary and farm workers handling automatic syringe injectors. Most of the time, these injuries are asymptomatic or cause self-resolving mild symptoms, but these injuries may lead to significant morbidity. The aim of the study was to evaluate hand function after inadvertent injection of a poultry influenza or cholera vaccine in patients admitted to our department with infection.
View Article and Find Full Text PDFPatient safety, self-injection, and B12 deficiency: a UK cross-sectional survey.
Br J Gen Pract
December 2022
NIHR Greater Manchester Patient Safety Translational Research Centre, University of Manchester, Manchester, and NIHR School for Primary Care Research, University of Manchester, Manchester.
Background: Individuals with vitamin B12 deficiency (including pernicious anaemia) often report being 'let down' or stigmatised by general practice systems and policy, and choose instead to self-medicate via injection; the association between this and perceptions of safe primary care in this group of people is unknown.
Aim: To examine the association between self-medication for vitamin B12 deficiency and patient-reported safety in primary care.
Design And Setting: A UK cross-sectional online survey.
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