AI Article Synopsis

  • Alterations in calcium and phosphorus levels, along with joint pain, are frequently seen in patients with end-stage renal disease.
  • Metastatic calcinosis cutis, a rare condition characterized by extensive soft tissue calcification around joints, often combines these symptoms, though its underlying mechanism remains unclear.
  • A case of a 26-year-old man exhibiting severe skin and joint calcification in multiple areas, including the shoulders, neck, hand, and penis, is presented.

Article Abstract

Alterations in calcium and phosphorus levels and joint pain are a common occurrence in end-stage renal disease patients. However, metastatic calcinosis cutis is a rare diagnosis that often combines these two findings, with extensive soft tissue calcification surrounding a large joint being the hallmark of this disease. The exact mechanism behind this clinical entity is unknown. The treatment and complications can be severe and disabling. Here, we discuss the case of a 26-year-old man presenting with unusually advanced skin and joint calcification of the shoulders, neck, hand, and penis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468049PMC
http://dx.doi.org/10.1080/08998280.2017.11929652DOI Listing

Publication Analysis

Top Keywords

metastatic calcinosis
8
calcinosis cutis
8
end-stage renal
8
renal disease
8
cutis end-stage
4
disease alterations
4
alterations calcium
4
calcium phosphorus
4
phosphorus levels
4
levels joint
4

Similar Publications

Background: Brain calcifications, found in various conditions, may be incidental or crucial for diagnosis. They occur in physiological changes, infections, genetic diseases, neurodegenerative conditions, vascular syndromes, metabolic disorders, endocrine disorders, and primary tumors like oligodendroglioma. While often incidental, their presence can be vital for accurate diagnosis.

View Article and Find Full Text PDF

Background: Vascular calcification is highly prevalent and associated with mortality in hemodialysis patients. However, extreme splanchnic arterial calcification in calciphylaxis with poor prognosis raises questions regarding the reliability of previous vascular calcification scoring methods. Therefore, this study aimed to examine the distribution characteristics of abdominal aortic branch calcification and identify a more reliable predictor of mortality in hemodialysis patients.

View Article and Find Full Text PDF

To analyze the clinical characteristics of patients with metastatic calcification undergoing maintenance dialysis. Patients diagnosed with metastatic calcification via 99mTc-MDP bone scintigraphy between June 2019 and March 2023 at our hospital were included in this study. All patients were followed from the time of diagnosis until death, loss to follow-up, or the study endpoint (July 2023).

View Article and Find Full Text PDF

A 13-year-old boy was referred to orthopedic surgery for chronic intermittent pain and swelling of the left knee. Initial imaging was consistent with osteochondritis dissecans of the femoral condyle. Follow-up imaging demonstrated unexpected progression, with a mass extending into the notch, replacing the anterior cruciate ligament, and eroding the femoral and tibial condyles.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!